Protein Info for H281DRAFT_05858 in Paraburkholderia bryophila 376MFSha3.1

Annotation: ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 TIGR02156: phenylacetate-CoA oxygenase, PaaG subunit" amino acids 27 to 315 (289 residues), 538.4 bits, see alignment E=1.7e-166 PF05138: PaaA_PaaC" amino acids 37 to 311 (275 residues), 324 bits, see alignment E=3.2e-101

Best Hits

Swiss-Prot: 67% identical to PAAA_ECOLI: 1,2-phenylacetyl-CoA epoxidase, subunit A (paaA) from Escherichia coli (strain K12)

KEGG orthology group: K02609, phenylacetic acid degradation protein (inferred from 97% identity to bgf:BC1003_3259)

MetaCyc: 68% identical to ring 1,2-phenylacetyl-CoA epoxidase PaaA subunit (Pseudomonas sp. Y2)
RXN0-2042 [EC: 1.14.13.149]

Predicted SEED Role

"Phenylacetate-CoA oxygenase, PaaG subunit"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.14.13.149

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MEX7 at UniProt or InterPro

Protein Sequence (332 amino acids)

>H281DRAFT_05858 ring-1,2-phenylacetyl-CoA epoxidase subunit PaaA (Paraburkholderia bryophila 376MFSha3.1)
MYTQSLDIPGNVASLDAGATSPEQTQFDAVMAADGKIEPQDWMPEAYRKTLVRQISQHAH
SEIVGMLPEGNWITRAPSLKRKAILLAKVQDEAGHGLYLYSAAETLGVSRDQLVAALHSG
KAKYSSIFNYPTPTWADVGVIGWLVDGAAIMNQIPLCRCTYGPYARAMIRICKEESFHQR
QGFDALMAMMSGTEAQRELVQQAVNRWWWPVLMMFGPSDKDSIHSNQSSKWGIKRISNDD
LRQKFVDATVDQAKVLGVTLPDPDLKWNEARGHYDYGDIDWEEFWRVVNGDGPCNRERLG
TRVKAHNEGAWVREAALAHAEKQRQRAQQHAA