Protein Info for H281DRAFT_05847 in Paraburkholderia bryophila 376MFSha3.1

Annotation: indolepyruvate ferredoxin oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 transmembrane" amino acids 747 to 768 (22 residues), see Phobius details PF02775: TPP_enzyme_C" amino acids 481 to 626 (146 residues), 27.3 bits, see alignment E=4.3e-10 PF01558: POR" amino acids 755 to 942 (188 residues), 64.1 bits, see alignment E=2.8e-21 PF20169: DUF6537" amino acids 981 to 1181 (201 residues), 220.7 bits, see alignment E=3.1e-69

Best Hits

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MEI4 at UniProt or InterPro

Protein Sequence (1199 amino acids)

>H281DRAFT_05847 indolepyruvate ferredoxin oxidoreductase (Paraburkholderia bryophila 376MFSha3.1)
MNAPLDAGQRASLEAALSSVTLDDKYTLERGRAYMSGIQALVRLPMLQQERDRAAGLNTA
GFISGYRGSPLGGLDQSLWKAKQHLASHQVVFQPGVNEDLAATAVWGSQQVNLYPSAKYD
GVFSMWYGKGPGVDRSGDVFKHGNSAGSSRHGGVLVLAGDDHAAKSSTLAHQSEHIFKAC
GLPVLFPSNVQEYLDFGLHGWAMSRYSGLWVAMKCVTDVVESSASVDIDPHRTQIILPED
FAMPEGGLNIRWPDPPLVQEARLLDYKWYAALAYVRANKLDRVEIDSPHARFGIMTGGKA
YLDVRQALTDLGLDDETCSRIGIRLYKVGCVWPLEAQGAQAFARGLDEILVVEEKRQILE
YAIKEELYNWPDAQRPRVFGKFDEKDGAGGEWSVPMGNWLLPAHYELSPAIIAKAIATRL
DKFDLPSDVRARIAARIAVIEAKEKALARPRVEVERKPWFCSGCPHNTSTNVPEGSRAMA
GIGCHYMTVWMDRSTSTFSQMGGEGVAWIGQAPFTNDKHVFANLGDGTYFHSGLLAIRAA
IASKANITYKLLYNDAVAMTGGQPVDGVLTVPQITHQLAAEGATKIAIVTDEPEKYSGNV
GLAPGIDIHHRDQLDEVQRQLREIPGTTILIYDQTCATEKRRRRKRGAYPDPARRVVINE
AVCEGCGDCSVKSNCLSVEPLDTEYGTKRQINQSTCNKDFSCVNGFCPSFVSVEGGQLRK
PKAASGIVADAMPPVPEPTLPSIARPYGVLVTGVGGTGVVTIGALLGMAAHLENKGVTVL
DVTGLAQKGGAVMSHVQIANNPGDIHATRIAMGEASLVIGCDAIVTASDECVSRMQAGRT
RVVLNSAHTPTAELIKNPNWRFPGSSTEADVRAGAGDECVDTVDANHFAVALLGDAIYTN
PFVLGYAWQRGWVPLTYQSLMRAIELNNVQVEKNRAAFEWGRRAAHDPVALRKYAQSQGQ
AGASDTPSGKIISLHTPKALDTLIDKRATYLAAWQNDAYADRYRALVSQVRVAESALDSI
DGQLPLTETVAKNLHKLMAYKDEYEVARLYSDPAFIEKLKASFEGDWKLHIHLAPPMFSK
KDAHGHLIKKKYGPWVFSAMHVLAKFKFLRGTALDVFGKTEERRTERALIGEYEALVREL
IGGLTVQNRDLAVELANLPDGIRGFGHIKENNLKGVRVKWNELLTRWRSPQAGTTQHAA