Protein Info for H281DRAFT_05843 in Paraburkholderia bryophila 376MFSha3.1

Annotation: two component transcriptional regulator, LuxR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 229 PF00072: Response_reg" amino acids 7 to 117 (111 residues), 61.2 bits, see alignment E=2.1e-20 PF08281: Sigma70_r4_2" amino acids 154 to 197 (44 residues), 25.8 bits, see alignment 1.3e-09 PF00196: GerE" amino acids 154 to 209 (56 residues), 46.9 bits, see alignment E=3.4e-16

Best Hits

Swiss-Prot: 39% identical to RCSB_ECOLI: Transcriptional regulatory protein RcsB (rcsB) from Escherichia coli (strain K12)

KEGG orthology group: K07687, two-component system, NarL family, captular synthesis response regulator RcsB (inferred from 93% identity to bgf:BC1003_3273)

Predicted SEED Role

"Two-component response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MG15 at UniProt or InterPro

Protein Sequence (229 amino acids)

>H281DRAFT_05843 two component transcriptional regulator, LuxR family (Paraburkholderia bryophila 376MFSha3.1)
MQEAVKVVIADDHPVILFGAEQALLKFPGMQVVARARQSTELIKILQTVECDVLVTDLAM
PGGQFGDGLPLIGYLRRNFAKVPIVVLTMLENAALLQRLRELGVTSVVNKSDDLSHIGLA
VQHVSRNLEYMSPSVKASLDALRMNAGGKSDEVMLSRRELEVVRLFVSGMTIKEISEQLN
RSIKTISTQKNTAMRKLGIDRDSELFQYAQSNGLLNLSSHSAGNGGDPP