Protein Info for H281DRAFT_05667 in Paraburkholderia bryophila 376MFSha3.1

Annotation: serine protease DegQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details amino acids 25 to 27 (3 residues), see Phobius details transmembrane" amino acids 12 to 24 (13 residues), see Phobius details TIGR02037: peptidase Do" amino acids 63 to 388 (326 residues), 432.5 bits, see alignment E=9e-134 PF00089: Trypsin" amino acids 117 to 277 (161 residues), 72.5 bits, see alignment E=1.1e-23 PF13365: Trypsin_2" amino acids 118 to 252 (135 residues), 122 bits, see alignment E=8.9e-39 PF00595: PDZ" amino acids 289 to 369 (81 residues), 44.7 bits, see alignment E=3.7e-15 PF13180: PDZ_2" amino acids 293 to 382 (90 residues), 59.6 bits, see alignment E=7.5e-20 PF17820: PDZ_6" amino acids 317 to 357 (41 residues), 43.5 bits, see alignment 5.8e-15

Best Hits

KEGG orthology group: K04772, serine protease DegQ [EC: 3.4.21.-] (inferred from 98% identity to bgf:BC1003_3146)

Predicted SEED Role

"Outer membrane stress sensor protease DegQ, serine protease" in subsystem Proteolysis in bacteria, ATP-dependent

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MFM5 at UniProt or InterPro

Protein Sequence (404 amino acids)

>H281DRAFT_05667 serine protease DegQ (Paraburkholderia bryophila 376MFSha3.1)
MLRRFWLFFAQAVTVLLALMFIIATLKPQWLQRQGQFGKQLAEPIVALREVAPGMGSGPA
TTSYADAAQKAMPAVVNVFSSKDGSLPPDPRAKDPLFRYFFGDKNNRKQREQPAANLGSG
VIVSSEGYILTNQHVVDGADQIEIALADGRTTNAKVIGIDPETDLAVLKVNMTNLPTITL
GRMEQTRVGDVVLAIGNPFGVGQTVTMGIVSALGRNHLGINTFENFIQTDAAINPGNSGG
ALVDVNGNLLGINTAIYSRSGGSLGIGFAIPVSTARSVLESIITTGSVTRGWIGVEPQDV
TPEIAESFGLEQKSGAIVAGVLKNGPADRAGIKPGDILMSVNGQEITDTTRLLNVIAQIK
PGTAAKVHLVRKNRELDLDVTIGKRPPPPKQPVEDSDQQDDDGG