Protein Info for H281DRAFT_05666 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Sec-independent protein translocase TatC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 transmembrane" amino acids 27 to 46 (20 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 121 to 142 (22 residues), see Phobius details amino acids 163 to 188 (26 residues), see Phobius details amino acids 200 to 217 (18 residues), see Phobius details amino acids 224 to 245 (22 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 17 to 234 (218 residues), 233.3 bits, see alignment E=1.5e-73 PF00902: TatC" amino acids 18 to 229 (212 residues), 244 bits, see alignment E=6.8e-77

Best Hits

Swiss-Prot: 52% identical to TATC_ECOLI: Sec-independent protein translocase protein TatC (tatC) from Escherichia coli (strain K12)

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 97% identity to bxe:Bxe_A0411)

MetaCyc: 52% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5ME08 at UniProt or InterPro

Protein Sequence (259 amino acids)

>H281DRAFT_05666 Sec-independent protein translocase TatC (Paraburkholderia bryophila 376MFSha3.1)
VSDPQKSQDEGAEETFISHLVELRDRIIRAGLAVIVVFVGLVYWAPDIFRLLARPLMQNL
PKDGKMIVTDVTGSFFVPMKVTMLVAFVIALPIVLYQIWAFVAPGLYQHEKKLVGPLVGS
SYTLFLCGMAFAYFVVFPTIFRVMAHYNAPLGAEMTTDIDNYLSFVLTMFIAFGVTFEVP
IVVVLLVRMNVVTLKKLKEIRPYVIVGAFVISAVVTPPDVFSQLILAIPLVVLYEAGIIA
ARLIVGKQPAVVEDATPPA