Protein Info for H281DRAFT_05635 in Paraburkholderia bryophila 376MFSha3.1

Annotation: putative ATP-binding cassette transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 583 transmembrane" amino acids 35 to 54 (20 residues), see Phobius details amino acids 76 to 98 (23 residues), see Phobius details amino acids 159 to 182 (24 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 303 to 328 (26 residues), see Phobius details PF06472: ABC_membrane_2" amino acids 28 to 303 (276 residues), 203.1 bits, see alignment E=8.8e-64 PF05992: SbmA_BacA" amino acids 35 to 353 (319 residues), 163.5 bits, see alignment E=1.4e-51 PF00005: ABC_tran" amino acids 403 to 532 (130 residues), 62.3 bits, see alignment E=1.2e-20

Best Hits

KEGG orthology group: K02471, putative ATP-binding cassette transporter (inferred from 96% identity to bug:BC1001_3215)

Predicted SEED Role

"ABC transporter, fused ATPase and inner membrane subunits (EC 3.6.3.27)" (EC 3.6.3.27)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.27

Use Curated BLAST to search for 3.6.3.27

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MG31 at UniProt or InterPro

Protein Sequence (583 amino acids)

>H281DRAFT_05635 putative ATP-binding cassette transporter (Paraburkholderia bryophila 376MFSha3.1)
MTTNTSASPALPPDEKVSAWSLIKPYWVSEERKTAWALLLAIIVMNLLVVWINVRLNRWS
ADFYNALQTKNVRDFPHLLMVFSGLAFGYIILAVYGRYMRQMLGFRWRQWLTTRYLNEWL
HDSAFYRIERDRLADNPDQRISDDLQSFATTTLSLTLDLLSTVVTLVSFITILWSLAGAL
TITLGGVPLHIPGYMVWAAALYAVVGSLVIQKVGHPLVPINYQAQKVEADFRFGLIRLRE
NAEQIAFYNGMDTEKKNAHSLFGRIRDNWWQVMKYTKRLTFVLSFYGQIAIIFPLVVAAP
RYFAGAFTFGVLMQISSAFGTVSDSFSWFINSYSTLVEWRATVNRLREFKRVVHAPRLKE
SVSPATAHGGINLHFVDADSLTTDRLKLALPNGTPLSRIRDIAIEPGSRWLVRGPSGSGK
STLMRALAGLWPFGDGSIDAPVNARMMFIPQVSYMPIGTLKAALTYPSAADTYTDDECRE
ALVTCHLSQYADRLQESGHWTRMLSPGEQQRLAAARVLLHKPDYLFLDEATSALDAENEA
RLYRLFTERLPKAAIVSVAHRESLAAFHDETLEVERASEAVAA