Protein Info for H281DRAFT_05588 in Paraburkholderia bryophila 376MFSha3.1

Annotation: protein translocase subunit secY/sec61 alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 448 transmembrane" amino acids 24 to 42 (19 residues), see Phobius details amino acids 76 to 99 (24 residues), see Phobius details amino acids 120 to 140 (21 residues), see Phobius details amino acids 152 to 172 (21 residues), see Phobius details amino acids 184 to 204 (21 residues), see Phobius details amino acids 213 to 234 (22 residues), see Phobius details amino acids 272 to 292 (21 residues), see Phobius details amino acids 319 to 340 (22 residues), see Phobius details amino acids 375 to 395 (21 residues), see Phobius details amino acids 401 to 420 (20 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 21 to 431 (411 residues), 428.4 bits, see alignment E=1.4e-132 PF00344: SecY" amino acids 77 to 419 (343 residues), 388.4 bits, see alignment E=1.4e-120

Best Hits

Swiss-Prot: 67% identical to SECY_ECOL6: Protein translocase subunit SecY (secY) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 99% identity to bge:BC1002_2877)

MetaCyc: 67% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MF13 at UniProt or InterPro

Protein Sequence (448 amino acids)

>H281DRAFT_05588 protein translocase subunit secY/sec61 alpha (Paraburkholderia bryophila 376MFSha3.1)
LANSPSLVKPGRSAAKFGDLRRRAVFLLLALIVYRIGAHIPVPGIDPDQLAKLFQSQSGG
ILGMFNMFSGGALSRFTIFALGIMPYISASIIMQLLAIVSPQLEALKKEGQAGQRKITQY
TRIFTVLLATFQAFGIAVALENQPALVIDPGMVFRLTTVVTLVTGTMFLMWLGEQITERG
LGNGISIIIFGGIAAGFPNAIGGLFELVRTGSMSIISAIIVVALIAAVTYLVVFIERGQR
KILVNYAKRQVGNKIYGGQSSHLPLKLNMSGVIPPIFASSIILFPATILNWFSSGSRTGW
FADTLHNVAEALKPGQPVYVLLYALAIVFFCFFYTALVFNSRETADNLKKSGAFVPGIRP
GDQTARYIDRILTRLTLAGAIYIVFVCLLPEFLVLRWNVPFYFGGTSLLIIVVVTMDFMA
QVQSYVMSQQYESLLKKANFKGGGVPMR