Protein Info for H281DRAFT_05562 in Paraburkholderia bryophila 376MFSha3.1

Annotation: indolepyruvate ferredoxin oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1163 transmembrane" amino acids 615 to 629 (15 residues), see Phobius details amino acids 738 to 762 (25 residues), see Phobius details amino acids 883 to 895 (13 residues), see Phobius details PF02775: TPP_enzyme_C" amino acids 491 to 563 (73 residues), 26.4 bits, see alignment 8.4e-10 PF01558: POR" amino acids 746 to 931 (186 residues), 84.8 bits, see alignment E=1.2e-27 PF20169: DUF6537" amino acids 957 to 1148 (192 residues), 152.5 bits, see alignment E=2.3e-48

Best Hits

KEGG orthology group: K04090, indolepyruvate ferredoxin oxidoreductase [EC: 1.2.7.8] (inferred from 69% identity to abb:ABBFA_002124)

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1163 amino acids)

>H281DRAFT_05562 indolepyruvate ferredoxin oxidoreductase (Paraburkholderia bryophila 376MFSha3.1)
MRIGEDDRVLEAGSQKGLTLDDKYVLDAGSGYMTGIQAIVRLALAQHRRDATAGLKTAAF
ISGYRGSPLGNLDTALWQAGKHLTAHDVVFQPGVNEDLAATAVWGSQQSQLAGQGKFDGV
VGWWYGKGPGVDRSGDVLRHANLAGTAAHGGAVALYGDDHSCKSSSIPHQSEHVMIGCGL
PIFYPTSVQEVLDFGVHAVAMSRATGLWTSMKLVSEIVETSASVDVDARRVSPNVTFDSP
VPSGGLNIRWPDRSLAQEERLYQYKLPAALAYARANAINQVAWPCANARIGIAASGKGYL
DTVEALRILGVEGEAARRIGLRLFRVGMIWPLEPAGLRVFAAGLQELIVVEEKRPILEAQ
IKDELYALPDDLRPRVIGKATDGHGEWSTPRSDAPLISHYELQPEPIAKMLASRLLRFEL
PEDIRQQIEQRVQAIEHAERESRKVIDIAERKAYFCSGCPHNTSTVVPTGSRSLGGIGCH
FLTLTMDRGTETFTQMGGEGANWVGTAPFTKESHVFTNLGDGTYFHSGYMAIRQAVAANV
NITYKILYNDAVGMTGGQHVDGQLSVGQLTRQLAAEGVGQQIVVSDEPGLIGEAGLAPGV
TVRHRSELDAVQRYLRTVTGVTALIYAQTCASEKRRRRKRNEYPDPDQRVFINSEICEGC
GDCSKKSNCLSVEPLETALGTKRQINQSSCNKDFSCTDGFCPSFVTVHARDVKRPAGFAG
LPDGWPVAPRMPALDLPLRIVVGGVGGTGVVTIGALLGTAAHLEGKAIRVMDMAGMAQKG
GTVYSYVQLALKDDAISATRVAAGQCDLLIGADAVVAGNGTTLSRMRSDALAIVNEDGSP
TSEFIRSRDWTAPVSDLLERLRARVNTGRVIALPAAQVATRILGDAIFANLMLLGMAWQA
GRIPLARASLERAIELNGTAVAKNLEAFRVGCHLVTEPALVRSILGHQSNEPVSQTLDDL
IEDRAARLKKYWKSSYANQYRRLLEPARRKMPEDLMITVATQLYRVMAYKDEYEVARMLV
SADFRRSIDDTFGAGVRLTYHLAPPTLGTGKDVKKRKYGQWVQWPMTILGKMQWLRETPL
DPFGRNDERRRERDWRDLYMSFVESLGSASSSRFDASVVREMARLPAEVRGFGHVKIQAM
DIASRRWTELASRLIPAAKQEEL