Protein Info for H281DRAFT_05475 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Choline dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 PF00732: GMC_oxred_N" amino acids 112 to 333 (222 residues), 72.3 bits, see alignment E=5.3e-24 PF05199: GMC_oxred_C" amino acids 421 to 537 (117 residues), 101.6 bits, see alignment E=5.7e-33

Best Hits

KEGG orthology group: None (inferred from 97% identity to bgf:BC1003_0613)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MQ56 at UniProt or InterPro

Protein Sequence (551 amino acids)

>H281DRAFT_05475 Choline dehydrogenase (Paraburkholderia bryophila 376MFSha3.1)
VSADDPHDAQLVPRGKNGRAPDVFRPAAWIPMREYPQDEAVDFAIVGTGAGGGTLACRLA
EKGFKVVAFDAGAWWRPLEEFASDETHQGKLFWTDERICDGGNPLHLGNNNSGKAVGGST
VHFAMVSLRFRPEWFRSRSLLGYGADWPLDWREMWRYYGEVEEALKIAGPVNYPWGPKRP
RYPYRAHELNASALVLARGCEALGIDWSPTPLATVSAPRGDAHPCVYRGFCVSGCATNAK
QSALVTWIPRAVRAGAEVRDLAMVGRIAMGHDGRASGVEYMREGRWQFQRARNVVVAGYA
IETPRLLLMSATERFPDGLANSSGLVGKNLMVQLNQAVWGTMDEEIRWYKGPPSLSLTEH
WNYEDKGKDFFGGYCYMSQGPLPVAWVSTQNGRGLWGQQLQDEMRKYNHQAGLKIVGEAM
PQERNRVTLADEKDQYGLPVARVTYSLCDNDKRLVRHSLDFMSLALEAAGARDIWRETDD
TCHLNGTARMGDDPATSVVNADCRSWDIDNLWICDGSVFPTVGGVNPSLTIQAIAMRTAD
RIEALAARGDL