Protein Info for H281DRAFT_05461 in Paraburkholderia bryophila 376MFSha3.1
Annotation: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 37% identical to UGL_BURCJ: Ureidoglycolate lyase (BceJ2315_61450) from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)
KEGG orthology group: None (inferred from 99% identity to bge:BC1002_5807)Predicted SEED Role
"Putative fumarylacetoacetate (FAA) hydrolase" in subsystem Aromatic amino acid degradation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (283 amino acids)
>H281DRAFT_05461 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) (Paraburkholderia bryophila 376MFSha3.1) MKLVSFEWQGRVGFGAVIDAGIVDLGQAFNGRYVSLKDLLAADAVGEAAELVSGRQADVQ MSDVTLLPVIPDPGKIWCCGLNYHEHVQETNREVTEQPTFFLRVASSQVGHEQAIVRPRE STQLDFEAEIAVVIGKGGRRIAPADAAQHIAGYACYNDGSVRDWQRHTSQWIPGKNFWRT GGFGPWMVTADEIPFDTRLKMVTRLNGQEMQNTTTDMMIHSIAKQIAYVSTIAPLEAGDV IVTGTPGGVGARRHPPVWMKAGDVVEIDVERIGVLRNPIADEQ