Protein Info for H281DRAFT_05410 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Ca2+:H+ antiporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details amino acids 35 to 54 (20 residues), see Phobius details amino acids 65 to 88 (24 residues), see Phobius details amino acids 101 to 122 (22 residues), see Phobius details amino acids 134 to 154 (21 residues), see Phobius details amino acids 167 to 185 (19 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 250 to 269 (20 residues), see Phobius details amino acids 281 to 304 (24 residues), see Phobius details amino acids 316 to 333 (18 residues), see Phobius details amino acids 340 to 359 (20 residues), see Phobius details PF01699: Na_Ca_ex" amino acids 35 to 187 (153 residues), 71.7 bits, see alignment E=3.4e-24 amino acids 218 to 358 (141 residues), 48.6 bits, see alignment E=4.3e-17

Best Hits

Swiss-Prot: 52% identical to Y4HA_SINFN: Putative ionic transporter y4hA (NGR_a03490) from Sinorhizobium fredii (strain NBRC 101917 / NGR234)

KEGG orthology group: K07300, Ca2+:H+ antiporter (inferred from 92% identity to bug:BC1001_5680)

Predicted SEED Role

"Calcium/proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJM8 at UniProt or InterPro

Protein Sequence (360 amino acids)

>H281DRAFT_05410 Ca2+:H+ antiporter (Paraburkholderia bryophila 376MFSha3.1)
MAKPPTVLPRWTLAVPLVAWIVLGAAYALPGNQLLLVLVGIALCAAVFTAVHHAEVVAHR
VGEPFGTLVLAVAVTVIEVALIVSVMLTSGPEKAGLARDTVFAAVMIVCNGIVGLCVLVG
GIRHREQDFQSRGAAAALAVLASLSVLTLVMPNYTTTSVGPMLSPSQLAFAGASSLVLYG
VFVFVQTVRHRDYFLADVPDEDVHAAPPSAGLALTSGGLLVACLVAVVLLAKVLSPVVET
AVQNAGAPPAVVGIIIAALVLLPEGLAAVRAARADRLQNSLNLALGSALASIGLTIPTVA
AVFLTTGQPLVLGLDGKETVLLVLTLIVGTLTLSTGRTTILQGAVHLSLFAAYLFLSFAP