Protein Info for H281DRAFT_05405 in Paraburkholderia bryophila 376MFSha3.1

Annotation: putative spermidine/putrescine transport system ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 PF00005: ABC_tran" amino acids 20 to 161 (142 residues), 137.8 bits, see alignment E=7.7e-44 PF08402: TOBE_2" amino acids 275 to 349 (75 residues), 26.7 bits, see alignment E=9.9e-10

Best Hits

Swiss-Prot: 46% identical to POTA_RUBXD: Spermidine/putrescine import ATP-binding protein PotA (potA) from Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)

KEGG orthology group: K02052, putative spermidine/putrescine transport system ATP-binding protein (inferred from 94% identity to bpy:Bphyt_4965)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1)" in subsystem Polyamine Metabolism (TC 3.A.1.11.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MHF6 at UniProt or InterPro

Protein Sequence (358 amino acids)

>H281DRAFT_05405 putative spermidine/putrescine transport system ATP-binding protein (Paraburkholderia bryophila 376MFSha3.1)
MTHLTLQAVTRRFGAAYAVDSVDLSVPDGKLVCFLGPSGCGKTTLLRMIAGLETPTSGSI
EFAGRDITRVPANQRDFGMVFQSLALFPHMSVAQNIAYPLKLRKTPKPEQARRIAELLEL
IQLPHMANRPVTQLSGGQRQRVAIARAIASQPKLLLLDEPLSALDAKLREAMQVEIRLLQ
QRLGITTIMVTHDQREAMTMADEIVVMEKGRIAQVGKPLDIYRDPVSEFVADFIGLGNIL
PVTYDGAGAVSLPGGVRIAVSQAARVPESTSDIRLLIRPEDVCVKSATGAAAGPNRLAGT
VTFIRDVGASLEATIDCAGFTLTAATTPRETPGLALGMPVLAELPPHACKLIAARAVQ