Protein Info for H281DRAFT_05375 in Paraburkholderia bryophila 376MFSha3.1

Annotation: peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 transmembrane" amino acids 38 to 57 (20 residues), see Phobius details PF13539: Peptidase_M15_4" amino acids 165 to 230 (66 residues), 45.6 bits, see alignment E=3.9e-16

Best Hits

KEGG orthology group: None (inferred from 96% identity to bug:BC1001_5648)

Predicted SEED Role

"Probable transmembrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>H281DRAFT_05375 peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK (Paraburkholderia bryophila 376MFSha3.1)
MRGASRSASVARGQLARSARISQSTAVDMKKLLARRRLLIFTTTGILATPPLVALALRGR
QLFQFDETARVPDEKIAALLNGEQLVPPPPLPPEVFATREVEQIRPALKDASRDWNLLDA
DFRTRLLLVYKIMHEQHGYEMALLEGYRSPERQNRLAQMGSNVTNAAAFQSYHQYGLAAD
NAFLRDGKLVISEKDPWAMRGYQLYGQTAEQVGLTWGGRWKMMDLGHVEYHKPGFVLGRG
H