Protein Info for H281DRAFT_05299 in Paraburkholderia bryophila 376MFSha3.1

Annotation: amino acid ABC transporter membrane protein 1, PAAT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 216 transmembrane" amino acids 15 to 42 (28 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 148 to 168 (21 residues), see Phobius details amino acids 187 to 209 (23 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 11 to 108 (98 residues), 90.4 bits, see alignment E=4.5e-30 PF00528: BPD_transp_1" amino acids 36 to 213 (178 residues), 86.7 bits, see alignment E=8.3e-29

Best Hits

Swiss-Prot: 37% identical to YECS_ECOL6: L-cystine transport system permease protein YecS (yecS) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 98% identity to bug:BC1001_5578)

MetaCyc: 37% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Glutamate transport membrane-spanning protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MGX2 at UniProt or InterPro

Protein Sequence (216 amino acids)

>H281DRAFT_05299 amino acid ABC transporter membrane protein 1, PAAT family (Paraburkholderia bryophila 376MFSha3.1)
MFSTTVFVQGMPLLLHAALATIGVSLTGLFIGFFVAVGVCAARLSPNRAARRFGGAYVFF
FRGVPMLVQLLLVYYLLPFAGINVSPLVAAISAVSLCSASYIAEILRGGFLSIPPGHIEA
ARMLGLSPFDTLRRILVPQAFRLTLPSLVNEMVLLIKASSLISVVGVAELTRTAQNIAAS
TYRPLEAYLAAGLIYFVICGALALIAHAAEFRLKHA