Protein Info for H281DRAFT_05221 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Saccharopine dehydrogenase, NADP-dependent

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 368 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details transmembrane" amino acids 304 to 324 (21 residues), see Phobius details PF02737: 3HCDH_N" amino acids 2 to 43 (42 residues), 23.9 bits, see alignment 1.6e-08 PF03807: F420_oxidored" amino acids 2 to 57 (56 residues), 25.3 bits, see alignment 8.8e-09 PF02558: ApbA" amino acids 3 to 77 (75 residues), 26.6 bits, see alignment E=1.9e-09 PF03435: Sacchrp_dh_NADP" amino acids 3 to 110 (108 residues), 62.3 bits, see alignment E=2.8e-20 PF02254: TrkA_N" amino acids 3 to 83 (81 residues), 32.2 bits, see alignment E=5.3e-11 PF01370: Epimerase" amino acids 5 to 71 (67 residues), 21.8 bits, see alignment E=5.1e-08 PF13460: NAD_binding_10" amino acids 8 to 91 (84 residues), 30.4 bits, see alignment E=1.6e-10 PF16653: Sacchrp_dh_C" amino acids 120 to 341 (222 residues), 63.1 bits, see alignment E=2e-20

Best Hits

KEGG orthology group: None (inferred from 96% identity to bug:BC1001_1514)

Predicted SEED Role

"Carboxynorspermidine dehydrogenase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MBG8 at UniProt or InterPro

Protein Sequence (368 amino acids)

>H281DRAFT_05221 Saccharopine dehydrogenase, NADP-dependent (Paraburkholderia bryophila 376MFSha3.1)
MKVAIVGAGLIGHTIAHMLRETGDYDVVAFDRDQHALDKLAAQGISTRRVDSADAAALRA
AVHGFDALINALPYYLAVNVAAAAKGAGVHYFDLTEDVRATHAIRAIADDADHAFMPQCG
LAPGFIGIAAHELANRFTEIRDVKMRVGALPQFPTNALKYNLTWSVDGLINEYCQPCEAI
RDSRTQWVQPLEGLEHFSLDGTEYEAFNTSGGLGTLCETLSGRVESLDYKSVRYPGHRNL
MQFLLEDLRLSSDRDTLKTIMRRSVPSTAQDVVLVFITVSGMRDGQLVQEVFTRKIFAKT
ICGVPMSAIQITTAGAMCAVLDLFREKKLPQRGFVRQEQVSLRDFLGNRFGQLYEGQALE
SLQSAATV