Protein Info for H281DRAFT_05087 in Paraburkholderia bryophila 376MFSha3.1

Annotation: exodeoxyribonuclease V alpha subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 774 PF13245: AAA_19" amino acids 224 to 369 (146 residues), 116.6 bits, see alignment E=3.2e-37 PF13604: AAA_30" amino acids 226 to 381 (156 residues), 90.7 bits, see alignment E=3.5e-29 PF00580: UvrD-helicase" amino acids 227 to 290 (64 residues), 27.7 bits, see alignment E=7.9e-10 PF05127: Helicase_RecD" amino acids 239 to 350 (112 residues), 29.2 bits, see alignment E=2.9e-10 PF13538: UvrD_C_2" amino acids 696 to 741 (46 residues), 48.4 bits, see alignment 2.4e-16 PF01443: Viral_helicase1" amino acids 696 to 743 (48 residues), 24.3 bits, see alignment 9.2e-09

Best Hits

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (774 amino acids)

>H281DRAFT_05087 exodeoxyribonuclease V alpha subunit (Paraburkholderia bryophila 376MFSha3.1)
MSTFNQTVSAPLQLDDLGVNLPAPADFSIALAEGFARRIGVLARRGGASTEAVRWAARAA
FAASRATAEGHVCVPLAALARRFEASTAEVRMALFASGMASDGSQAASALRPLVIDAQGR
LYLARYYEYERRLARALVAHAGAPMRATVLESARGLGDAGERFAEHAAGTLPASARGRAG
GEKGTAFDSEAAVDTSANADTTQTLHQRLVRYFGPPKDDEVDWQRVAAVMALSGRLTIVS
GGPGTGKTTTVVGVLACLLDARADLRIALAAPTGKAAQRMQEALLARAGDLPPELAARLP
QTSYTLHRLLGSGPSGRFRHHRDNPLPYDVVVIDEASMIDVAMAAHLLDAIAPHTRLVML
GDKDQLAAVEAGAVFAELSARPAFSAQGVKRIAGALGIGEARLAQALPRLAEDVDEQPER
FWQTGRSADYASDLFDAPPDDLFAAPDAASNVASNSASNSVSNSVSNSVSNVGDPRSADP
HGADASAASARSGTAGHESQSPLADCVVWLERNYRFGLESPIGRLSLAIRNGAASAALDV
LLDDATQHSASLYEDAHVALAERTVERLAAGFAPYANALAAALAAETPDPLPLFDALNRF
RVLCATRLGPRGVDQVNALMAAQVRRSAGVTLAVGAQWFAGRPVMVTRNDYALGLFNGDI
GIALPGAGGALRVYFRTADGGLRAVSPAALPPHDTAFALTVHKSQGSEFEHAVLMLPSTF
SRVLSRELVYTAITRARERVEVIGASAVLAQAIATPTQRDSGLAARIEEASRGR