Protein Info for H281DRAFT_05086 in Paraburkholderia bryophila 376MFSha3.1

Annotation: DNA helicase/exodeoxyribonuclease V, beta subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1233 TIGR00609: exodeoxyribonuclease V, beta subunit" amino acids 16 to 1226 (1211 residues), 831 bits, see alignment E=1.1e-253 PF00580: UvrD-helicase" amino acids 19 to 445 (427 residues), 172.7 bits, see alignment E=3.4e-54 PF13245: AAA_19" amino acids 25 to 92 (68 residues), 28.6 bits, see alignment 3.6e-10 PF13361: UvrD_C" amino acids 685 to 842 (158 residues), 43.3 bits, see alignment E=8.7e-15 PF12705: PDDEXK_1" amino acids 1001 to 1195 (195 residues), 29.4 bits, see alignment E=2e-10

Best Hits

KEGG orthology group: K03582, exodeoxyribonuclease V beta subunit [EC: 3.1.11.5] (inferred from 90% identity to bpy:Bphyt_1614)

Predicted SEED Role

"Exodeoxyribonuclease V beta chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1233 amino acids)

>H281DRAFT_05086 DNA helicase/exodeoxyribonuclease V, beta subunit (Paraburkholderia bryophila 376MFSha3.1)
MSGALHRHALAAEELDVFACSLDGVNQIEASAGTGKTWNICALYVRLLLEKNLNADQILV
VTFTKAATAELHERIRGRLAELHRAIEVDDDGGDPFIRRLFETTLAPERGIDREAALKVV
RRALRTFDQAAIHTIHAFCQRALQEAPFAAAMPFAFEMEADDAALRFELATDFWREQVEP
VAHAHPAFAAWLVAKRAGPASLDEQLARRLKKPLAQLRWGVIDAEASADPRAGFDAACEL
WHAERDAIMALLEQAQDRLSKTTHKPDHVSAAIAAWTEYFAQGDCHAPPPRAALKLTASA
LKKATKVKFEPPEHVFFEHAEALAAAVVAAEAAQRARWLALMQTWLDYAPAELVARKRTR
RVVSFDDLLSNLYRALAAHPWLADALRARYPAALIDEFQDTDPLQFAIFSRIFAPAGPLF
LVGDPKQAIYSFRAADLHTYLAARASASARYTLAVNQRSTAPIVEACNRVFEANPQAFVL
DGLDYQPVRAGERRRPPLTDPDAEAGDFRVWTLPQGESALTKRQAQREASEACAAEIVRL
LRGAREGTVTIGDAPLAPGNIAVLVQTHKQGSLIKRVLAAWGVGSVELAQASVFATLDAE
QIERVLAAVDTPGDLRRLRAALATDWLGLDAAALWRLEQVADAPAVADDPAHAADAMGWV
ERFSRYRTLWHERGFAVMWRTLMRELRVAQRLVAAPDGERRLTNVNHLAELVQARAASQP
GIAPTLRWLAAQRTQGGGEEAQLRLESDRNLVQIVTVHKSKGLEYAVVFCPFLNDGGLRE
PPSSGLPDAREYHDASGDAVLHYGCDDDEAERATRHAAREQAAERARLVYVALTRAVYRC
YLVAGTYLSSRSTKESRRSVLNWLVAGGGYEFDGWLAEPPDEAALSARWQALAGHPIALQ
PLPKVERRAPLESMHESSADKRARSNRRPLRDQWRMASFSGLIVAGSKAEDAQPPVEEVR
PDHDEIADALVATPVTVSEPALEAQSLAADDILAFPRGAAAGECLHRMFELADFSDPQSW
PDAIRGALHERPAPASPELAPRLPAMMHKLLADVVSTELVPGMTLARLDPRRRLNELEFL
FAAPSLDFAVLRELLVAHGYPDVALEPGVLRGFVKGFIDMIVEHDGRFWIVDWKSNHLGD
TEQDYAAAPVEAAMASHAYHLQALLYTVALHRYLKTRVRDYSYETHIGGYLYLFVRGVRP
HWRDAEAQAGVHVRRPAFELVALLDAAMIGGAA