Protein Info for H281DRAFT_05085 in Paraburkholderia bryophila 376MFSha3.1

Annotation: DNA helicase/exodeoxyribonuclease V, gamma subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1125 PF04257: Exonuc_V_gamma" amino acids 2 to 343 (342 residues), 262.7 bits, see alignment E=4.7e-82 TIGR01450: exodeoxyribonuclease V, gamma subunit" amino acids 2 to 1071 (1070 residues), 698.1 bits, see alignment E=1.1e-213 PF17946: RecC_C" amino acids 817 to 1066 (250 residues), 139 bits, see alignment E=1.9e-44

Best Hits

KEGG orthology group: K03583, exodeoxyribonuclease V gamma subunit [EC: 3.1.11.5] (inferred from 91% identity to bpy:Bphyt_1613)

Predicted SEED Role

"Exodeoxyribonuclease V gamma chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MBA9 at UniProt or InterPro

Protein Sequence (1125 amino acids)

>H281DRAFT_05085 DNA helicase/exodeoxyribonuclease V, gamma subunit (Paraburkholderia bryophila 376MFSha3.1)
MLQLFYSNRYETLVGALLDDLAQAPSDAWTAQPVIVPSAAVRRRLELDIAARQGVCANVS
FGYLAQWLWAQIGGVIEVPRHSPFAPDRLVWRCYRLLGDAHESLPWNASPRLRTYLDAAD
PSMRYELARRVATVLDHYLTYRPEWLLQWQKGGSIFAGGGADDTGPRLVGASDAAREDER
WQAALWRAVLTELAGNEQTPDAALPPAYRFLDEIGTLDLDAIAKANWPEAVSVFALPTMP
PLHVALLRALSRWVDVRLYVMNPCREFWFDVVSEGRVQALDAAGQLDYQEVGHPLLAEWG
RQTQAQLHMLHELTESAASGETGEFSENPEPSWLAAVQNGILDLRPETEADELPYERGIE
VHVCHSLSRQLEVLHDRLLGWFDEFDDLQPSDVLVAVSDLGAAGPLIDAVFGTTPSGATR
RIPYRITGLPPSQANPVARLVLDWLALPERSVGAPDLIEWLRVDAVAVRYGIDASSLEAA
QEWLAAAGARRGLSPAEPSGEHVPVARHTFADALTRLYLGYAMPEGGEPVDAWLPVEGAD
GSDAELLGRLSRFVDDIDSFAVRCATEQTPAEWTQLLLETLAQCFDGGVEFAESLAAVRD
AIDKMSDAMQAGAHEVAMPAAVVRVALTEALDDPARGGVPWGSVTFSSLTSLRGLPYRVV
CLLGMDDGVLPSLARADEFDLMAAFGKAGDRQRRDDERNLFLDLLLAARSRLFIAYTGRS
IRDNAPLPPAALVDELLDHLAQVSAGEGASPAQLEEARQAFIVDHPLQAFASEYFTAQPD
LFTYDADRAELATLLAAPQQQAAAPFFDHPLPAEDAAPVGFDEFVRFWRHPARALLRDRL
GIVLSDAQGELLDTEPFELDYTGRDALAGRLLPVLLDADIEDDDLMFDRVRRVAEASPEL
PGGATGAVWRARELGALRQLADSVRREVASGVERLPFVLDIAPRWPDNADIAGELFGVHD
AELREAALTPLQLHGTLNLLTETGQVIFRYAKPTARDYLSAWLAHLAYCAALPDGPRRTV
WHGSGESFELAPVAAPLEELAPLAALFRSGRRLPLRFFPKSAWAKVSESDSAAQGVWIND
RVRGESDDPALRIALRGTPLTLDEPFGSLAAIVFKPLLQHLRSVS