Protein Info for H281DRAFT_05079 in Paraburkholderia bryophila 376MFSha3.1

Annotation: small conductance mechanosensitive channel

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 889 transmembrane" amino acids 18 to 37 (20 residues), see Phobius details amino acids 49 to 67 (19 residues), see Phobius details amino acids 220 to 241 (22 residues), see Phobius details amino acids 272 to 289 (18 residues), see Phobius details amino acids 300 to 321 (22 residues), see Phobius details amino acids 341 to 358 (18 residues), see Phobius details amino acids 368 to 391 (24 residues), see Phobius details amino acids 416 to 438 (23 residues), see Phobius details amino acids 450 to 471 (22 residues), see Phobius details amino acids 491 to 512 (22 residues), see Phobius details amino acids 532 to 553 (22 residues), see Phobius details amino acids 583 to 605 (23 residues), see Phobius details amino acids 612 to 639 (28 residues), see Phobius details PF21088: MS_channel_1st" amino acids 586 to 627 (42 residues), 32.2 bits, see alignment 8.7e-12 PF00924: MS_channel_2nd" amino acids 629 to 694 (66 residues), 58.7 bits, see alignment 5e-20

Best Hits

KEGG orthology group: None (inferred from 88% identity to bgf:BC1003_2021)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (889 amino acids)

>H281DRAFT_05079 small conductance mechanosensitive channel (Paraburkholderia bryophila 376MFSha3.1)
MQSCPSRRESEAAPSNGGLFAIHAAFPRLFARIGFLIRRGACPPGASRFGVWPVALLVAL
FLWTAWLPTSAHAADAGAGTPVIPALQSLINSATVAPASSASGASAAEAASAPSPASQAE
IARSLDSVIATLDNDRQRSALVAQLKKLRDVSRTVGPLAPAPAQQSPGLLGAIASGIASF
ESDVHEGRTPVRYWGGRFNAAGNELYTIISGQGQESLGRILFSMFAMLAGWGACAAALIY
LQHRLYRRLGIVIGLNPNPTTRELLIFALRRVGPWVIAFVAALLFVRAMPDALGRTLGMV
VAYAIVAGAVFSAICLIMFSLFGSGHRRTAVRLLIDHARRLLFAVGVCGALGDAAVNYDV
AHQMGSNLAALVSTAANMTAAVLTGYFALAFRRPVAHLIRNRPYDQRNDHKAATDAFDVL
AALWHVPVLVLATASVVATLGGSGSSENVLQISVVTALLLVLAFFLSAIVLRMTRPRSAR
ARRRSPYLTRLLRFCGTLLTLFIWLFFFELAARLWGVSLAAVVEENVAARGIAHAVTAIV
ATVFIAWLLWILVDTAITEALNPGSARNKSRGPSMRARTMLPLVRNVLLVSIMTIAGIVT
AANLGINVTPLLAGAGVIGLAIGFGAQSLVTDLITGLFIIIEDTISVGDWIDVDGGHAGT
VEHLSIRTVRLRDGQGAIHAIPFSQIKIVKNLSRDFAYAVFEVRMSFSTDVDEITQLIRE
VGADLMADFRYRREMLGPIEVWGLDRFDPNWMVVKGQIKTRPLQQWSVARAFNLRLKRKM
DEAGIEIPVPQMRLFTSSKDSEGQPLHDEDVLGARPHEHADARADAHAEARAGQHEHAVG
HQEKSPPIRGAHPAVVARDVSHEPRPAPPPTGQTAPIPPQIPTAGEGKA