Protein Info for H281DRAFT_05074 in Paraburkholderia bryophila 376MFSha3.1

Annotation: protease I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 193 PF01965: DJ-1_PfpI" amino acids 4 to 184 (181 residues), 144.9 bits, see alignment E=1e-46 TIGR01382: intracellular protease, PfpI family" amino acids 5 to 187 (183 residues), 208.1 bits, see alignment E=3.3e-66

Best Hits

KEGG orthology group: K05520, protease I [EC: 3.2.-.-] (inferred from 96% identity to bug:BC1001_1352)

Predicted SEED Role

"ThiJ/PfpI family protein"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.-.-

Use Curated BLAST to search for 3.2.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (193 amino acids)

>H281DRAFT_05074 protease I (Paraburkholderia bryophila 376MFSha3.1)
MAAKKILFLTGDFAEDYETMVPFQALQAVGHVVDAVCPDKKAGDRIKTAIHDFEGDQTYT
EKPGHLFALNASFEDADPRQYDALAIAGGRAPEYLRLNPKVIELVRQFAEAGKPIAAICH
AAQLLAAADVIRGKRISAYPACAPEVKLAGGEFADIPVDAAITDGNFVTAPAWPAHPEWL
RQFLVLLGTRIEL