Protein Info for H281DRAFT_04977 in Paraburkholderia bryophila 376MFSha3.1

Annotation: voltage-dependent potassium channel beta subunit, animal

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 323 PF00248: Aldo_ket_red" amino acids 16 to 309 (294 residues), 224.6 bits, see alignment E=7.5e-71

Best Hits

Swiss-Prot: 48% identical to KCAB3_XENLA: Voltage-gated potassium channel subunit beta-3 (kcnab3) from Xenopus laevis

KEGG orthology group: None (inferred from 96% identity to bgf:BC1003_2274)

Predicted SEED Role

"Aldo/keto reductase (EC 1.1.1.91)" (EC 1.1.1.91)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.91

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MCB7 at UniProt or InterPro

Protein Sequence (323 amino acids)

>H281DRAFT_04977 voltage-dependent potassium channel beta subunit, animal (Paraburkholderia bryophila 376MFSha3.1)
MNYRRLGRSGLQVSELSIGSWVTYGNQVDHRAARESLAAARDAGVNFFDNAEVYAGGKSE
EIMGQALKELAWPRVSYVVSTKFFWGLEEAPNQYHTLNRKYLLNAIDSSLKRLQLDYVDL
VFCHRPDPNTPVEETVWAMSDMITRGKALYWGTSEWSADEIRAAYDIAERHHLHKPVMEQ
PQYNLFHRKRVEQEYKRLYEDIGLGLTTWSPLASGLLTGKYRNGVPADSRAQLQGYDWLR
KQVTDAGKNNVVGKLGEVADELGCTVGQLAIAWILKNPHVSTVITGASRVEQISENMKSA
EVAEQITPEIKERIEGIFGDVYD