Protein Info for H281DRAFT_04936 in Paraburkholderia bryophila 376MFSha3.1

Annotation: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 21 to 485 (465 residues), 332.4 bits, see alignment E=2.3e-103 PF02321: OEP" amino acids 73 to 273 (201 residues), 85.1 bits, see alignment E=2.7e-28 amino acids 303 to 474 (172 residues), 80 bits, see alignment E=1e-26

Best Hits

KEGG orthology group: None (inferred from 71% identity to bgl:bglu_1g30270)

Predicted SEED Role

"Outer membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MD54 at UniProt or InterPro

Protein Sequence (491 amino acids)

>H281DRAFT_04936 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family (Paraburkholderia bryophila 376MFSha3.1)
MMFNRPSSFALAAAALLSSLSVLPGCTVGPDYHGAPPVAQDARGAAFVRTPAAGTTAAPA
PREWWLALNDPQLNDLIAAALAHSPDVHIAQARLRESRAQLQSQRADALPKLSVNAAALR
TREPDLSALSSAGSSGGSSGSSGRGPLQLYTAGFDASWEIDLFGGTRRAIEAASANAEAV
DADLADTQVSLAAEVAQTYIDLRDQQTRLELARRQADIEQKMLTLTQQRRERGTAADIDV
ERLTTQVENTRSTLIPLDAQMSDSLDRLAVLTGRAPGALDQQLASARPLPPMPATVPIGD
PSAMLQRRPDIRAAERRLASSNAQIGEHVADFFPKVTLFGDIGFSASDPGHLIRKSNFSW
ITAPYLQWNAFDFGRTLGSVHAAEASRDEAEARYTKAVLGALQDANSSLSRYGHQREHVV
TLLKVETSATHSAALMRQRYTAGVATLIDLLDTQRQEFSAQQNVVAGQAELLKDFVSLQK
SLGIGWEAPQG