Protein Info for H281DRAFT_04879 in Paraburkholderia bryophila 376MFSha3.1

Annotation: putative MFS transporter, AGZA family, xanthine/uracil permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 460 transmembrane" amino acids 40 to 61 (22 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 119 to 140 (22 residues), see Phobius details amino acids 151 to 170 (20 residues), see Phobius details amino acids 188 to 209 (22 residues), see Phobius details amino acids 216 to 242 (27 residues), see Phobius details amino acids 263 to 283 (21 residues), see Phobius details amino acids 312 to 332 (21 residues), see Phobius details amino acids 340 to 340 (1 residues), see Phobius details amino acids 342 to 364 (23 residues), see Phobius details amino acids 368 to 389 (22 residues), see Phobius details amino acids 400 to 428 (29 residues), see Phobius details amino acids 439 to 459 (21 residues), see Phobius details PF00860: Xan_ur_permease" amino acids 37 to 420 (384 residues), 238.2 bits, see alignment E=6.7e-75

Best Hits

Swiss-Prot: 72% identical to GHXQ_ECOLI: Guanine/hypoxanthine permease GhxQ (ghxQ) from Escherichia coli (strain K12)

KEGG orthology group: K06901, putative MFS transporter, AGZA family, xanthine/uracil permease (inferred from 99% identity to bug:BC1001_1252)

MetaCyc: 72% identical to guanine/hypoxanthine transporter GhxQ (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-562; TRANS-RXN0-578

Predicted SEED Role

"Xanthine/uracil permease family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MFX1 at UniProt or InterPro

Protein Sequence (460 amino acids)

>H281DRAFT_04879 putative MFS transporter, AGZA family, xanthine/uracil permease (Paraburkholderia bryophila 376MFSha3.1)
MMEPHAQPLSEAGAESFDTKGFLDRYFEISSRGSSQRQEIVAGITTFLAMVYSVFVVPGM
FGKAGFDTSAVFVAVCLTTAFGSLLMGVWARLPIAIGCAISLTAFTAFGLVLGKGLHPTV
ALGAVFLMGVVFTAISVTGVRSWILRNLPTGIAHGTGIGIGLFLLLIAANDVGLVVKNPG
AGLPVSLGNITALPALMSVAGLAAIFGLVRRRVPGSILIVIIGISAIALLVDPAVSFHGV
FAVPSLSAPGHESLIGAMDIKGALSMAVLPSVLALVMTAVFDATGTIRAVAGQAGQLDEN
GRIINGGRALTADSVSSIFSGLLGGAPAAAYIESTVGVAAGAKTGMAAAVVGLLFLGVMF
FSPLASLVPSYATAPALMYVGLLMLSNVSKLHMDDMVDAMSGLMCAVFIVLTANIVTGIM
LGFATLVIGRVVSGEYRKLNVGTVAIAIVLVGFYLGGWAI