Protein Info for H281DRAFT_04868 in Paraburkholderia bryophila 376MFSha3.1

Annotation: formimidoylglutamate deiminase (EC 3.5.3.13)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 TIGR02022: formiminoglutamate deiminase" amino acids 6 to 464 (459 residues), 595.6 bits, see alignment E=3.1e-183 PF01979: Amidohydro_1" amino acids 54 to 421 (368 residues), 82.9 bits, see alignment E=1.3e-27

Best Hits

KEGG orthology group: K05603, formimidoylglutamate deiminase [EC: 3.5.3.13] (inferred from 86% identity to bug:BC1001_1261)

Predicted SEED Role

"Formiminoglutamic iminohydrolase (EC 3.5.3.13)" in subsystem Histidine Degradation (EC 3.5.3.13)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>H281DRAFT_04868 formimidoylglutamate deiminase (EC 3.5.3.13) (Paraburkholderia bryophila 376MFSha3.1)
MTQAKQTLFAEHAYLPGGWRRDVLLEWDVDGNLTTVEPDTRDVPASVARAAGPVMPGMPN
LHSHAFQRAMAGLTEYRGSSATGAADNFWSWRDLMYRFAARISPEGLASVAQWLYIEMLK
AGYTSVCEFHYVHHTPDGGRYGNPAELAQRVVDAASASGIGMTMLPVLYQYSGFGARAPR
DDQRRFINTPGSLLELLGALRAARPENAALRYGVAPHSLRAVSEQSLRELLGGLDGSAPV
HIHIAEQTAEVDACVETEGARPVQWLLDRFDVDSRWCLVHATHVDANETLALARSGAVAG
LCLTTEANLGDGLFPAQEYLDAKGRIGVGSDSHIGVDWRAELRLLEYGQRLTRRQRNVLA
SAQTPYVADRLFDAALEGGAQATGRATGALQVGHRADWLVLDPNHASIAEHAPSAWLSGV
VFCEHGETPIRDVYAGGDKVVDNRRHRDEEGAYARYRVALADLLK