Protein Info for H281DRAFT_04708 in Paraburkholderia bryophila 376MFSha3.1

Annotation: regulatory inactivation of DnaA Hda protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 247 TIGR03420: DnaA regulatory inactivator Hda" amino acids 4 to 226 (223 residues), 239.2 bits, see alignment E=2e-75 PF00308: Bac_DnaA" amino acids 96 to 205 (110 residues), 27 bits, see alignment E=2e-10

Best Hits

KEGG orthology group: K10763, DnaA-homolog protein (inferred from 95% identity to bgf:BC1003_0472)

Predicted SEED Role

"Chromosomal replication initiator protein DnaA" in subsystem DNA-replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M7T3 at UniProt or InterPro

Protein Sequence (247 amino acids)

>H281DRAFT_04708 regulatory inactivation of DnaA Hda protein (Paraburkholderia bryophila 376MFSha3.1)
VLRQLTLDLGTPPPSTFDNFFAGANAELVTRLRELDGALAAGPVADRTFYIWGEAGSGRT
HLLQALVHEAPPGHARFAGPQSSLAAFSFDPRVALYAIDDCDGLSAAQQIAVFNLFNEVR
AHPTSALVATGNAAPIGMTVREDLRTRLGWGLVFHLAPLPDEGKAAVLKHAARERGIMLA
DDVPAYLLTHFRRDMPSLMALLDALDRFSLEQKRAVTLPLLRTMLASPGADGPAASSAAS
SKIDPHG