Protein Info for H281DRAFT_04706 in Paraburkholderia bryophila 376MFSha3.1

Annotation: poly(A) polymerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 532 TIGR01942: poly(A) polymerase" amino acids 69 to 509 (441 residues), 508.6 bits, see alignment E=6.6e-157 PF01743: PolyA_pol" amino acids 100 to 244 (145 residues), 125.7 bits, see alignment E=2.1e-40 PF12627: PolyA_pol_RNAbd" amino acids 271 to 331 (61 residues), 73.3 bits, see alignment E=1.6e-24 PF12626: PolyA_pol_arg_C" amino acids 385 to 499 (115 residues), 146.1 bits, see alignment E=7.1e-47

Best Hits

KEGG orthology group: K00970, poly(A) polymerase [EC: 2.7.7.19] (inferred from 96% identity to bug:BC1001_0458)

Predicted SEED Role

"Poly(A) polymerase (EC 2.7.7.19)" in subsystem Polyadenylation bacterial (EC 2.7.7.19)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M8M0 at UniProt or InterPro

Protein Sequence (532 amino acids)

>H281DRAFT_04706 poly(A) polymerase (Paraburkholderia bryophila 376MFSha3.1)
VIKKLIRKLFGQDTASADDTVPAEADSDEPGSAPARNAAGAAGTGRARRKPVRNGAPAKT
VRDPDVPVIIPHDVHGIDPTLISRNAIRVTEGLQQAGHRAFIVGGAVRDLLLGIKPKDFD
VATDATPEQVQKLFRRARIIGRRFQIVHVQFGQEIIETSTFRALVDPPAADAAPPRRLKR
DELDRRTHAVDASGRVLRDNVWGEQHEDATRRDFTINAMYYDPATETVLDYHNGMADVRA
RLLRMIGDPATRYREDPVRMLRVVRFAAKLDFEIEDATRAPIAEMADLINNVPAARLFDE
MLKLMLSGHALACLKRLRQEGLHHGLLPLLDVVLEQPTGEKFITLALTNTDARVRAGKPV
SPGFLFATLLWHDVQQRWQKFEANGEYPVPALHRAMDEVLDMQTEKLAIHKRFSSDMREI
WGLQLRLEKRSGRSALKLLEHQRFRAGYDFLLLRCESGELDESVGAWWTEFIEGDIAARE
TLLTQGGKDRSPRKRRRRSSGARNRKSGDGMEGGTPAERTDAEAGHEGPHED