Protein Info for H281DRAFT_04666 in Paraburkholderia bryophila 376MFSha3.1

Annotation: MFS transporter, MHS family, proline/betaine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 425 transmembrane" amino acids 21 to 49 (29 residues), see Phobius details amino acids 57 to 83 (27 residues), see Phobius details amino acids 90 to 109 (20 residues), see Phobius details amino acids 115 to 136 (22 residues), see Phobius details amino acids 156 to 178 (23 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 271 to 293 (23 residues), see Phobius details amino acids 305 to 325 (21 residues), see Phobius details amino acids 332 to 351 (20 residues), see Phobius details amino acids 370 to 393 (24 residues), see Phobius details amino acids 400 to 418 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 20 to 223 (204 residues), 65.6 bits, see alignment E=4.2e-22 amino acids 234 to 416 (183 residues), 29.8 bits, see alignment E=3e-11 PF07690: MFS_1" amino acids 34 to 284 (251 residues), 60.8 bits, see alignment E=1.1e-20 amino acids 266 to 417 (152 residues), 57.9 bits, see alignment E=8.8e-20

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 96% identity to bgf:BC1003_0427)

Predicted SEED Role

"Citrate-proton symporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M895 at UniProt or InterPro

Protein Sequence (425 amino acids)

>H281DRAFT_04666 MFS transporter, MHS family, proline/betaine transporter (Paraburkholderia bryophila 376MFSha3.1)
MNATTAASLAGSRRNSWRAVIAASIGNALEWFDLVVYGFFAVVIAKLFFPAGNDTVSLLL
TLGTFGVSFFMRPLGAIVIGAYADRAGRKAALTLSILLMMGGTLIIAVLPTYRSIGIAAP
VILVIARLMQGFSAGGEFGSATAFLAEHVPGRRGFFASWQVASQGLTTLLAAGFGVALTG
NLTPDQMASWGWRVPFFFGLLIGPVAWYIRTKLDETPEFLAAETTSTPLRDTFTSQKLRL
LIAIGAVVLGTVSTYLVLFMPTFGVKQLGLAPSVAFSAIALTGLIQMVFAPVVGHLSDRH
GRTTIMLISAVLLLVLIYPAFVYLVAHPTFGTLIALQVVLGFLMTGYFAALPGLLSEMFP
VQTRTTGMSLAYNIAVTVFGGFGPFIIAWLIGFTGSKAAPSYYLIFAALLSVAALIAARR
KLGFR