Protein Info for H281DRAFT_04653 in Paraburkholderia bryophila 376MFSha3.1

Annotation: NAD(P) transhydrogenase subunit alpha

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 PF05222: AlaDh_PNT_N" amino acids 4 to 136 (133 residues), 149.3 bits, see alignment E=7.8e-48 PF01262: AlaDh_PNT_C" amino acids 140 to 378 (239 residues), 219.9 bits, see alignment E=2.6e-69

Best Hits

KEGG orthology group: K00324, NAD(P) transhydrogenase subunit alpha [EC: 1.6.1.2] (inferred from 96% identity to bxe:Bxe_A4008)

Predicted SEED Role

"NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)" in subsystem Phosphate metabolism (EC 1.6.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.1.2

Use Curated BLAST to search for 1.6.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M7P1 at UniProt or InterPro

Protein Sequence (380 amino acids)

>H281DRAFT_04653 NAD(P) transhydrogenase subunit alpha (Paraburkholderia bryophila 376MFSha3.1)
MHIGVPAETRAHETRVAATPETVKKYVSQGHRVTIQSGAGAGASFPDDAFTAAGAEIVDA
ASAFGAELVLKVQSPTEAELPLLKRGAVLVGMLDPFNAENALKLAAAGVTAFALEAAPRT
TRAQSLDVLSSQANIAGYKAVLLAATLYPRFMPMLMTAAGTVKAARVLILGAGVAGLQAI
ATAKRLGAVIEASDVRPAVKEQIESLGAKFLDVPYETDEEREAAQGVGGYARPMPPSWLQ
RQSALVHERAKQADVVISTALIPGRAAPTLISVETVQAMKPGSVLVDLAAGRGADYEGQR
GGNCPLTEADKVVVKHGVTIVGYTNLASMVPADASSLYARNLLDFLKLIVTKEGALNIDL
ADDIVAATLLARDGEVARKA