Protein Info for H281DRAFT_04628 in Paraburkholderia bryophila 376MFSha3.1

Annotation: FdhD protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00129: formate dehydrogenase family accessory protein FdhD
  • amino acids 29 to 267 (239 residues), 203 bits, E=2.4e-64
• PF02634: FdhD-NarQ
  • amino acids 34 to 271 (238 residues), 226.7 bits, E=1.9e-71

Best Hits

Swiss-Prot: 81% identical to FDHD_BURMA: Sulfur carrier protein FdhD (fdhD) from Burkholderia mallei (strain ATCC 23344)

KEGG orthology group: K02379, FdhD protein (inferred from 96% identity to bpy:Bphyt_0665)

Predicted SEED Role

"Formate dehydrogenase chain D (EC 1.2.1.2)" in subsystem Formate hydrogenase (EC 1.2.1.2)

MetaCyc Pathways

• formate oxidation to CO₂ (1/1 steps found)
• superpathway of C1 compounds oxidation to CO₂ (8/12 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• oxalate degradation VI (1/4 steps found)
• oxalate degradation III (1/5 steps found)
• purine nucleobases degradation I (anaerobic) (6/15 steps found)

KEGG Metabolic Maps

• Glyoxylate and dicarboxylate metabolism
• Methane metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.2.1.2

Use Curated BLAST to search for 1.2.1.2

Sequence Analysis Tools

See A0A2Z5M8X5 at UniProt or InterPro

Protein Sequence (279 amino acids)

>H281DRAFT_04628 FdhD protein (Paraburkholderia bryophila 376MFSha3.1)
LNELETAGQPGAVERQVHRHRGAAVETVTDHVGQEWPVALVFNGISHAVMMCTPRDLEAF
AVGFAISEGIVGRGSDIQDIEVELHDDGELPHAEVQLQVVQQAFVALKEKRRALAGRTGC
GVCGIESIDLLDLKPERVPDTGFLQRLAPDAIARAARELPQHQALTRLTGGLHAAAWCDA
AGAIRYAFEDVGRHNALDKLIGQLVLDRVDTKEGFVFLSSRASYELVRKAARVDVPMVAT
ISAPSSLAIAIARKAGVRLVSFCRETSYVDYDTAQPSQS