Protein Info for H281DRAFT_04614 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Predicted lipid-binding transport protein, Tim44 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 329 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 95 to 115 (21 residues), see Phobius details amino acids 121 to 142 (22 residues), see Phobius details PF04280: Tim44" amino acids 202 to 325 (124 residues), 65 bits, see alignment E=4.3e-22

Best Hits

KEGG orthology group: None (inferred from 92% identity to bug:BC1001_0365)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M7Q1 at UniProt or InterPro

Protein Sequence (329 amino acids)

>H281DRAFT_04614 Predicted lipid-binding transport protein, Tim44 family (Paraburkholderia bryophila 376MFSha3.1)
MSDSAVLSPRKVKRSLARRIGLIAMVGLIVAGSVASLDAEARRMGGGRSFGRQSNTVQQQ
AAPSQPSPSNQGMQRAQPAPAPAPAPAPQPNRSRWLGPIAGLAAGLGIAALLSHFGLGGA
FAGAMANIIVIALLVMVGIWLIRRFMGRKRDTSQPAYAGQSPSLNSGATGYTQEPRYSAP
PTGSYLEPQGNPLTTPSINTTPSVPAGFDSEAFLRNAKVYFVRLQAAWDVGNIDDIREFT
TPEMFAEIRVDLASRGAETNQTDVVQLNADLLGVEERANEYFASVRFSGLIRETPGAAAQ
PFVEVWNLSKANRPGEGWLLAGIQQLAQH