Protein Info for H281DRAFT_04578 in Paraburkholderia bryophila 376MFSha3.1

Annotation: NADH dehydrogenase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 691 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 39 to 59 (21 residues), see Phobius details amino acids 87 to 108 (22 residues), see Phobius details amino acids 120 to 137 (18 residues), see Phobius details amino acids 143 to 162 (20 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details amino acids 221 to 237 (17 residues), see Phobius details amino acids 258 to 276 (19 residues), see Phobius details amino acids 288 to 309 (22 residues), see Phobius details amino acids 316 to 337 (22 residues), see Phobius details amino acids 344 to 364 (21 residues), see Phobius details amino acids 383 to 404 (22 residues), see Phobius details amino acids 424 to 445 (22 residues), see Phobius details amino acids 501 to 525 (25 residues), see Phobius details amino acids 567 to 588 (22 residues), see Phobius details amino acids 639 to 661 (23 residues), see Phobius details amino acids 667 to 689 (23 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 9 to 685 (677 residues), 807.2 bits, see alignment E=7e-247 PF00662: Proton_antipo_N" amino acids 71 to 121 (51 residues), 78.5 bits, see alignment 4.2e-26 PF00361: Proton_antipo_M" amino acids 137 to 419 (283 residues), 267.8 bits, see alignment E=1.7e-83 PF01010: Proton_antipo_C" amino acids 492 to 587 (96 residues), 26.9 bits, see alignment E=5.3e-10

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 96% identity to bgf:BC1003_2309)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5ME14 at UniProt or InterPro

Protein Sequence (691 amino acids)

>H281DRAFT_04578 NADH dehydrogenase subunit L (Paraburkholderia bryophila 376MFSha3.1)
MSTILNENLLLAIPLAPLAGSLIAGLFGKAVGRAGAHSVTILGVAISFVLSMMVFFQVLD
GASFNATVYEWMTIGKTKFEVGFLVDSLTAMMMCVVTFVSLMVHIYTIGYMADDDGYQRF
FSYISLFTFSMLMLVMSNNFLQLFFGWEAVGLVSYLLIGFYFTRQSAVYANMKAFIVNRI
GDFGFLLGIGLLFAFAGSMNYGDVFAKRTELAALSFPGTDWGLLTVACICLFIGAMGKSA
QFPLHVWLPDSMEGPTPISALIHAATMVTAGIFMVTRMSPLFELSDSALSFVMVIGAITA
LFMGFLGIVQNDIKRVVAYSTLSQLGYMTVALGASAYPVAVFHLMTHAFFKALLFLGAGS
VIIGMHHDQDMRNMGGLRKYMPITWITSLVGSLALIGTPFFSGFYSKDSIIDAVKLSHLP
GSGFAYFAVVASVFVTALYSFRMYFMVFHGKERFRDPKHPESPMGAEAAAHGHGNGHDDH
GHGHGHDDHGHAHEPHETPWVVWLPLVLLAIPSVVIGAIAIGPMLFGDFFQHGVAFDKVI
FIGENHPALHEMAEEFHGWAAMGLHSVAGLPVWLALAGVVVAWFLYLVRPELPATIKRAF
GPIYTLLDNKYYMDKINEVVFARGAVAIGRGLWKEGDVVVIDGIVNGSARFIGWFAGVIR
FLQSGYIYHYAFAMIIGMLGLLTLFVTLGGK