Protein Info for H281DRAFT_04550 in Paraburkholderia bryophila 376MFSha3.1

Annotation: RNA polymerase, sigma-24 subunit, RpoE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 187 TIGR02937: RNA polymerase sigma factor, sigma-70 family" amino acids 22 to 180 (159 residues), 65.7 bits, see alignment E=2e-22 PF08281: Sigma70_r4_2" amino acids 124 to 172 (49 residues), 61.5 bits, see alignment E=4.7e-21 PF04545: Sigma70_r4" amino acids 131 to 176 (46 residues), 35.7 bits, see alignment E=5e-13

Best Hits

KEGG orthology group: K03088, RNA polymerase sigma-70 factor, ECF subfamily (inferred from 94% identity to bph:Bphy_2023)

Predicted SEED Role

"DNA-directed RNA polymerase specialized sigma subunit, sigma24-like"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MC74 at UniProt or InterPro

Protein Sequence (187 amino acids)

>H281DRAFT_04550 RNA polymerase, sigma-24 subunit, RpoE (Paraburkholderia bryophila 376MFSha3.1)
MASDKELADFLAGVERRAFKQTVYAVRDDDASLDIVQDAMIKLAEKYGDRPAAELPLLFQ
RILQNAMHDHFRRAKVRNTWVSLFSSLGNADDDEFDPLETFEAQQGSAGAESNEQKLERE
QVLQMIDDEIRKLPARQREAFLMRYWEDMDVAETAAAMGCSEGSVKTHCSRATHTLAQAL
KAKGITL