Protein Info for H281DRAFT_04417 in Paraburkholderia bryophila 376MFSha3.1

Annotation: two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 437 transmembrane" amino acids 7 to 26 (20 residues), see Phobius details amino acids 30 to 48 (19 residues), see Phobius details PF11808: PhoR" amino acids 5 to 90 (86 residues), 62 bits, see alignment E=1.2e-20 TIGR02966: phosphate regulon sensor kinase PhoR" amino acids 94 to 424 (331 residues), 452.3 bits, see alignment E=4.7e-140 PF00512: HisKA" amino acids 206 to 270 (65 residues), 72.9 bits, see alignment E=3.5e-24 PF02518: HATPase_c" amino acids 317 to 426 (110 residues), 99.6 bits, see alignment E=2.9e-32 PF13581: HATPase_c_2" amino acids 320 to 409 (90 residues), 29 bits, see alignment E=1.8e-10

Best Hits

KEGG orthology group: K07636, two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC: 2.7.13.3] (inferred from 96% identity to bgf:BC1003_2462)

Predicted SEED Role

"Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MD11 at UniProt or InterPro

Protein Sequence (437 amino acids)

>H281DRAFT_04417 two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR (Paraburkholderia bryophila 376MFSha3.1)
MNIIWARSIVSIVLLAILCVVVGALVNVKAALILAVVMLLLQSFFGTFHKERLWRLLDAP
VYGEVPSAPGIWGEIYYRLHKLAKRWHAQVRQVEQQHSRFIQAIQASPNGVAMLDDHDQI
EWCNAISEVHFGLDAKRDLRQHITHLVRQPDFVRYLNSHHYEEMLIMRGMGEKRQNVLSV
QVFPYGENRKLVLSQDITELERTDAMRRDFVANVSHELKTPLTVLSGFLETMRELPLAET
ERARYLELMEQQASRMRHIVNDLLVLAKLEGDNKPPSDQMIDMRAVLRHLRDDAESLSSD
HHKITFDADEGLTVTGVETEILSALGNLVTNAIRYTPDGGAIKVSWQAQAGAAVFSVTDS
GLGIPAADIPRLTERFYRVDRSRSRDTGGTGLGLAIVKHVLQRHDAQLDVKSEEGRGSTF
TVRFPVYRTTRRQPAHA