Protein Info for H281DRAFT_04400 in Paraburkholderia bryophila 376MFSha3.1

Annotation: membrane-bound lytic murein transglycosylase D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF01464: SLT" amino acids 118 to 220 (103 residues), 87.1 bits, see alignment E=6.4e-29 PF01476: LysM" amino acids 341 to 384 (44 residues), 24.3 bits, see alignment 2.5e-09 amino acids 418 to 457 (40 residues), 27.2 bits, see alignment 3.1e-10

Best Hits

KEGG orthology group: K08307, membrane-bound lytic murein transglycosylase D [EC: 3.2.1.-] (inferred from 96% identity to bug:BC1001_2508)

Predicted SEED Role

"Membrane-bound lytic murein transglycosylase D precursor (EC 3.2.1.-)" (EC 3.2.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.2.1.-

Use Curated BLAST to search for 3.2.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MCD4 at UniProt or InterPro

Protein Sequence (549 amino acids)

>H281DRAFT_04400 membrane-bound lytic murein transglycosylase D (Paraburkholderia bryophila 376MFSha3.1)
MRFIFSALLVLTLAACASQGPTTSSPTTATNPASQQAVADALRKTATAKETINVDQGSVT
QLTSADADLWGRIRRGFQMPDLQTDLVDMQVNWYAQRPDYVQRMTERSQKYLYHIVEELE
ARHMPTELALLPFIESAYSPQALSVAKAAGMWQFMPGTGRTYNLKQNMWQDERRDVLAST
SAALDYLSRLHDMFGDWQLALAAYNWGEGNVQRAIARNEAAGLPTDYLSLRMPNETRNYV
PKLQAVKNIVSNPQMYGLALPSIPNHPYFVTVTTSHDIDVDMAAKLANLSLDEFRSLNPS
FRKPVILGATQPQILLPFDNASAFERNLKTYSGSLSSWTTYTVTERSAPAAIAQKIGVDA
DTLMEVNKIPVGMRLKPGSTIVVPRGSDDDEDISADVAESAVLAMEPDVPDTRKMLIRVR
RNQSMAAIALRYGVSVGQLKSWNRTHRDSVTRGQVIVLHVPVGRTVPSEPGPERIATDVQ
GGGVQKIGTRVGGSKSESHNDSKKGRGHSAVVKVSEPVAKAGKSKASVAPAGKVTKVSAS
TSSKTKKSK