Protein Info for H281DRAFT_04254 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Holliday junction DNA helicase subunit RuvA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 193 TIGR00084: Holliday junction DNA helicase RuvA" amino acids 1 to 189 (189 residues), 176 bits, see alignment E=3e-56 PF01330: RuvA_N" amino acids 1 to 62 (62 residues), 80.7 bits, see alignment E=1.3e-26 PF14520: HHH_5" amino acids 72 to 129 (58 residues), 60.6 bits, see alignment E=3.3e-20 PF07499: RuvA_C" amino acids 147 to 191 (45 residues), 52.5 bits, see alignment 1.1e-17

Best Hits

Swiss-Prot: 97% identical to RUVA_PARXL: Holliday junction ATP-dependent DNA helicase RuvA (ruvA) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K03550, holliday junction DNA helicase RuvA (inferred from 96% identity to bpy:Bphyt_3345)

Predicted SEED Role

"Holliday junction DNA helicase RuvA" in subsystem DNA-replication or RuvABC plus a hypothetical

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MDP9 at UniProt or InterPro

Protein Sequence (193 amino acids)

>H281DRAFT_04254 Holliday junction DNA helicase subunit RuvA (Paraburkholderia bryophila 376MFSha3.1)
MIGRIAGVLLEKNPPHLLVDCNGVGYEVDVPMSTFYNLPSTGERVVLLTQMIVREDAHLL
YGFGTTEERSTFRELLKISGIGARMALAVLSGMSVHELSQTVTLQDAARLTRVPGIGKKT
AERLLLELKGKLGADLGAMAGAASASDHASDILNALLALGYSEKEALAAIKNVPAGTGVS
EGIKLALKALSKA