Protein Info for H281DRAFT_04221 in Paraburkholderia bryophila 376MFSha3.1

Annotation: hemolysin III

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 39 to 59 (21 residues), see Phobius details amino acids 77 to 93 (17 residues), see Phobius details amino acids 99 to 119 (21 residues), see Phobius details amino acids 128 to 148 (21 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 186 to 205 (20 residues), see Phobius details PF03006: HlyIII" amino acids 5 to 198 (194 residues), 146.2 bits, see alignment E=6.2e-47 TIGR01065: channel protein, hemolysin III family" amino acids 5 to 204 (200 residues), 222.6 bits, see alignment E=1.9e-70

Best Hits

Swiss-Prot: 48% identical to HLY3_BACCE: Hemolysin-3 from Bacillus cereus

KEGG orthology group: K11068, hemolysin III (inferred from 97% identity to bpy:Bphyt_3310)

Predicted SEED Role

"COG1272: Predicted membrane protein hemolysin III homolog"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MF02 at UniProt or InterPro

Protein Sequence (206 amino acids)

>H281DRAFT_04221 hemolysin III (Paraburkholderia bryophila 376MFSha3.1)
VHVGERFNSITHLVGAVLSVAGLATLVTMGAVEGDAYKVVSFSVYGAMLFVLYAISTLYH
SVRSPRIKAVLQKCDHSAIYLLIAGSYTPFTLVTLRGPWGWSLFGVSWGLAALGIVQELT
LGRRTRSVSMVLYVLMGWLALVAVRPLVQALPAAGTAWLVAGGVIYSAGIYFFINDERIR
HGHGIWHLFVLAGSLCQFVSVARYVA