Protein Info for H281DRAFT_04202 in Paraburkholderia bryophila 376MFSha3.1

Annotation: type IV pilus assembly protein PilA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 transmembrane" amino acids 37 to 62 (26 residues), see Phobius details TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 40 to 61 (22 residues), 29.6 bits, see alignment (E = 2.2e-11) PF07963: N_methyl" amino acids 40 to 60 (21 residues), 24.6 bits, see alignment (E = 1.4e-09) PF00114: Pilin" amino acids 69 to 206 (138 residues), 49.5 bits, see alignment E=7.5e-17

Best Hits

KEGG orthology group: K02650, type IV pilus assembly protein PilA (inferred from 89% identity to bxe:Bxe_A0677)

Predicted SEED Role

"Type IV pilin PilA" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MFU5 at UniProt or InterPro

Protein Sequence (207 amino acids)

>H281DRAFT_04202 type IV pilus assembly protein PilA (Paraburkholderia bryophila 376MFSha3.1)
MIVTLPYSPYSQSALISQSRLTRARWSSTFARACRRLGLGFTLIELMIVLAIVGVIAAYA
IPAYQDYLARSRVGEGLSLAASARLAVSENAASGNAFSGGYASPPATRNVESVHVDDDTG
QITVAFTTRVAPSGSNTITLVPSVPDNVDAPTARVALTKGSVQAGALAWECFAGGKTASS
LPAPGAGPSPVNAPTLSSNLAPPECRT