Protein Info for H281DRAFT_04159 in Paraburkholderia bryophila 376MFSha3.1
Annotation: sorbitol-binding protein /mannitol-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K10227, sorbitol/mannitol transport system substrate-binding protein (inferred from 98% identity to bgf:BC1003_2831)MetaCyc: 61% identical to polyol ABC-type transporter periplasmic substrate-binding protein (Pseudomonas fluorescens)
7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]; 7.5.2.M2 [EC: 7.5.2.M2]
Predicted SEED Role
"Various polyols ABC transporter, periplasmic substrate-binding protein" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization
Isozymes
No predicted isozymesUse Curated BLAST to search for 7.5.2.M2
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5MDX7 at UniProt or InterPro
Protein Sequence (440 amino acids)
>H281DRAFT_04159 sorbitol-binding protein /mannitol-binding protein (Paraburkholderia bryophila 376MFSha3.1) MKPALKSALKAVSAGAAACFALSASAATVTIATLNNPDMIELKKLSPEFEKANPDIKLNW VILEENVLRQRATTDITTGSGQFDVMTIGAYETPQWGKRGWLTPLTNLPADYDLNDVVKT ARDGLSAGGQLYALPFYVESSMTYYRKDLFAAKGLKMPDQPTYDQIAQFADKLTDKANGM YGICLRGKAGWGENMAYGTTVVNTFGGRWFDEKWHAQLTSPEWKKAITFYVDLLKKNGPP GASSNGFNENLTLMSSGKCAMWIDATVAAGMLYNKQQSQIADKVGFAAAPIAVTPKGSHW LWAWALAIPKSSKQADAAKKFITWATSKQYIELVAKDEGWASVPPGTRQSTYARPEYKQA APFGDFVLKAIETADPEHPTAKPVPYTGVQFVGIPEFQSFGTVVGQSISGAIAGQMTVDQ ALAAGQATADRAVKQAGYQK