Protein Info for H281DRAFT_03955 in Paraburkholderia bryophila 376MFSha3.1

Annotation: transporter, CPA2 family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 585 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 32 to 52 (21 residues), see Phobius details amino acids 59 to 78 (20 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 120 to 139 (20 residues), see Phobius details amino acids 151 to 173 (23 residues), see Phobius details amino acids 185 to 209 (25 residues), see Phobius details amino acids 221 to 238 (18 residues), see Phobius details amino acids 244 to 262 (19 residues), see Phobius details amino acids 274 to 292 (19 residues), see Phobius details amino acids 298 to 321 (24 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 358 to 378 (21 residues), see Phobius details amino acids 426 to 448 (23 residues), see Phobius details amino acids 467 to 485 (19 residues), see Phobius details amino acids 516 to 539 (24 residues), see Phobius details amino acids 545 to 564 (20 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 13 to 377 (365 residues), 210 bits, see alignment E=2.6e-66

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 97% identity to bug:BC1001_2663)

Predicted SEED Role

"POTASSIUM/PROTON ANTIPORTER ROSB" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MCY0 at UniProt or InterPro

Protein Sequence (585 amino acids)

>H281DRAFT_03955 transporter, CPA2 family (Paraburkholderia bryophila 376MFSha3.1)
MHEGIGFIQDLAVVMALAGVVTVLFHRLKQPVVLGYIAAGVIIGPYTPPFQLIHDEQTIK
TLGELGVVFLMFSLGLEFSLRKLFKVGATAIVAALSEIVLMLWLGYEIGSAFGWSPMDSL
FLGAILAISSTTIIVKALSELGLKRESFAQLVFGILIVEDILAIAMLVLLSGIAQTGQLS
AGVAAVTLGKLLLFMTVSLVVGILVVPRALNYVALARSDEMLLVAVLGFCFGFCLLVVKL
DYSIALGAFLIGAIMAESRHLHRIEHLIAPLRDAFSAIFFVTIGLMLNPAVLVDYAWPIA
VITVAVIVGKIVSCGLGTFLAGKDGRTAMRVGMTVSQIGEFSFIIASLGLTLKVTSAFLY
PIAVAVSALTTLFTPYLIRAADPLTRRFADAMPRTLVNVFGMYSQWLSSLSTESGEPTLF
SMTRRIILQIAVNLALVAAIFLIVSYGAPYISTVLTRWVSSEPMQRVVLWSVALLVSMPF
LVAVYRKTKSLALLLAEVSVQPATAGRFTSALRYAISDLVPVVCMVGVFLLVAALSGGIL
PPTGLLAAVLICAALLLALVWRWCVKIHAAMQIALRETFDEQPDP