Protein Info for H281DRAFT_03828 in Paraburkholderia bryophila 376MFSha3.1

Annotation: MFS transporter, ACS family, hexuronate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 15 to 33 (19 residues), see Phobius details amino acids 55 to 77 (23 residues), see Phobius details amino acids 84 to 112 (29 residues), see Phobius details amino acids 142 to 162 (21 residues), see Phobius details amino acids 173 to 192 (20 residues), see Phobius details amino acids 237 to 256 (20 residues), see Phobius details amino acids 272 to 298 (27 residues), see Phobius details amino acids 310 to 326 (17 residues), see Phobius details amino acids 332 to 353 (22 residues), see Phobius details amino acids 365 to 384 (20 residues), see Phobius details amino acids 396 to 418 (23 residues), see Phobius details PF07690: MFS_1" amino acids 23 to 383 (361 residues), 194.3 bits, see alignment E=2.8e-61 PF00083: Sugar_tr" amino acids 51 to 415 (365 residues), 43 bits, see alignment E=3e-15

Best Hits

KEGG orthology group: K08191, MFS transporter, ACS family, hexuronate transporter (inferred from 88% identity to bph:Bphy_5675)

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MNN5 at UniProt or InterPro

Protein Sequence (429 amino acids)

>H281DRAFT_03828 MFS transporter, ACS family, hexuronate transporter (Paraburkholderia bryophila 376MFSha3.1)
MQTAVLGLARTASRYRWTVCALLFFATVINYMDRQILGLLAPLLQHDIGWSQVQYGRIVI
AFSAFYAVGLLCFGRIVDWLGTRISYALAMLIWSIAAMLHAAVGSVTGFAMVRALLGIGE
GGNFPAAIKTTAEWFPRRERALATGIFNSGANIGAVFAPAIIPPLALAFGWRSAFVIIGA
LGIVWLAVWFAFYRSAEPRSHDDDLEEARDEVEALDAANANARAPGWGVLIRKRQTWAFL
IGKFLTDPVWWFYLFWLPKWLNESRGMDMQHIGLPLVCIYAMTTVGSIGGGWLSSALLRA
GWSVNAARKTAMFICACCVLPIAFVSQVDNLWGAVAIVGLAAAAHQGWSANLFTTASDLF
PKRALGAVVGIGGMAGSIGGVLFSEVIGQVLQRTGHYWVLFAIGALAYLIAFAVMHMLTP
RMAPAKFEA