Protein Info for H281DRAFT_03566 in Paraburkholderia bryophila 376MFSha3.1
Annotation: alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K00830, alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase [EC: 2.6.1.44 2.6.1.45 2.6.1.51] (inferred from 96% identity to bpy:Bphyt_6959)Predicted SEED Role
"Serine--glyoxylate aminotransferase (EC 2.6.1.45)" in subsystem Photorespiration (oxidative C2 cycle) or Serine-glyoxylate cycle (EC 2.6.1.45)
MetaCyc Pathways
- formaldehyde assimilation I (serine pathway) (10/13 steps found)
- glycine biosynthesis III (1/1 steps found)
- L-serine biosynthesis II (3/4 steps found)
- photorespiration I (6/9 steps found)
- photorespiration III (6/9 steps found)
- photorespiration II (6/10 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.51
Use Curated BLAST to search for 2.6.1.44 or 2.6.1.45 or 2.6.1.51
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5ML98 at UniProt or InterPro
Protein Sequence (406 amino acids)
>H281DRAFT_03566 alanine-glyoxylate transaminase / serine-glyoxylate transaminase / serine-pyruvate transaminase (Paraburkholderia bryophila 376MFSha3.1) MLKLDFHPAGRHFLQIPGPSPVPDRILRAMSYPTIDHRGPEFGELGLKVLDGIKKIFKTQ HPVVIYPASGTGAWEAALSNTLSPGDHVLMFETGHFATLWKKMAESLGLKPEFLGLPGIE GWRRGVQPQMIEARLREDTQHSIKAVCVVHNETSTGVTSDIAAVRRAIDAAGHPALLLVD TISGLACADYRHDEWGVDVTVSGSQKGLMLPPGISFNAISPKAVAASKHAKLPRSFWDWS EIVEMNKTGYWPYTPNTNLLYGLHEALEMILGEGLDNVFARHERLAEATRRAVRAWGLEI QCADPAVYSPVLTGVMMPDGVDADAVRKLIYERFDMSLGTGLGKMKGRMFRIGHLGDCND LMLLATLAGCEMGLRLAGVPLKGSGLPAAMEWLSEPTQASGLKAAA