Protein Info for H281DRAFT_03563 in Paraburkholderia bryophila 376MFSha3.1

Annotation: FAD/FMN-containing dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1006 PF01565: FAD_binding_4" amino acids 61 to 195 (135 residues), 127.7 bits, see alignment E=7e-41 PF02913: FAD-oxidase_C" amino acids 286 to 534 (249 residues), 168.6 bits, see alignment E=5.2e-53 PF13183: Fer4_8" amino acids 595 to 672 (78 residues), 37.1 bits, see alignment 9.3e-13 PF13534: Fer4_17" amino acids 598 to 673 (76 residues), 30.7 bits, see alignment 8.9e-11 PF02754: CCG" amino acids 774 to 854 (81 residues), 16.5 bits, see alignment E=2e-06

Best Hits

KEGG orthology group: K06911, (no description) (inferred from 92% identity to bgf:BC1003_4690)

Predicted SEED Role

"Glycolate dehydrogenase (EC 1.1.99.14), subunit GlcD" in subsystem Glycolate, glyoxylate interconversions or Photorespiration (oxidative C2 cycle) (EC 1.1.99.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.1.99.14

Use Curated BLAST to search for 1.1.99.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1006 amino acids)

>H281DRAFT_03563 FAD/FMN-containing dehydrogenase (Paraburkholderia bryophila 376MFSha3.1)
MTNPTSALLVKPIHLVPSTARLMTPLAQHLRKSLRGDVLFDAASRGRYATDASIYQIMPV
GVVVPRDQDDLRIALDIARSEKVPLLARGAGTSQCGQTVGEALVIDTSKWLNNIVDFNLE
ARTVTVEPGVVLDHLNAWLKPHGLWFPVDVSTAAQCTIGGMAGNNSCGSRSIEYGNMVHN
VEAIDAILADGTEARFASLRDAPQGARLQQIFEGVRQIAQRERDEIVARVPKVLRRVAGY
NIDLFDCQNPRAYTDDGVANLAHLLVGSEGTLAFSRQLTLKLAPLPAHKTLGVVNFPTFW
QSMDLTQHIVKLKPVAVELVDRTMIDLAMSNPAFRPVVEKALVGEPQAVLLVEFAGESRD
AQLESLRQLSELMADLGLPGSVVEMPDANAQKALWEVRKAGLNIMMSMKGDGKPVSFIED
CAVPLEHLAEYTSQLTEVFHRHGTEGTWYAHASVGTLHVRPILDMRRDGAVKMRAIAEQA
AALVREYKGAYSGEHGDGLCRGEWVAWQYGPKLNQAFSEIKALFDPDNRFNPDKMVRPPK
MDDPRYFRFAPGYQERPIEPALDWSAWNVERDPLTGRETAPGSGNDLAGGLAKAVEMCNN
NGHCRKFDAGTMCPSYRVTKDEQHVTRGRANTLRLAISGQLGEAGLASDEVKDTLDLCVS
CKGCKRDCPTGVDMAKFKIEARAARVKRHGLTLRDKLVAFMPRYAAAASRMPGLIAVADN
VPLVSSLFKRAVGFASERSLPRFRKSFLSSASPTVNAHGATLKEVLLFVDTFNNSMEPEN
ARAAQKVLEAAGYTVHFNMREGERPVCCGRTFLAAGLVDEAKHEARRMLDLFNPFVERGV
PIVGLEPSCLLSLRDEFLHYGFGDEAQQLAKQAFLFEEFLVREEKAGRLELALKPLDTPQ
ALVHGHCHQKAFDAFTPVQTVLKWIPELKVSTVESSCCGMAGSFGYEAEHYATSQAMAEL
SLLPAVRKIDGNTVMVADGTSCRHQIHDGAGVEAIHVARVLAMALQ