Protein Info for H281DRAFT_03550 in Paraburkholderia bryophila 376MFSha3.1

Annotation: two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1172 transmembrane" amino acids 29 to 54 (26 residues), see Phobius details amino acids 332 to 351 (20 residues), see Phobius details amino acids 356 to 382 (27 residues), see Phobius details PF00512: HisKA" amino acids 551 to 616 (66 residues), 60.5 bits, see alignment 2e-20 PF02518: HATPase_c" amino acids 663 to 778 (116 residues), 78.2 bits, see alignment E=9.7e-26 PF00072: Response_reg" amino acids 938 to 1047 (110 residues), 78.4 bits, see alignment E=7.1e-26

Best Hits

KEGG orthology group: K07677, two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC: 2.7.13.3] (inferred from 77% identity to bgf:BC1003_4678)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1172 amino acids)

>H281DRAFT_03550 two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC (Paraburkholderia bryophila 376MFSha3.1)
MQKILDRSQESLEYAFASLAKTAKRQQRVYLATIGSLMLMVAVFALVIAVVAAFKQLEYR
RTFTSQNATDLSLLLHREESFLRRAEFTLDYYYGATDVRRAPEAVEQSIAQTGAARGTVD
RVDAEFDVVIGQSTRAAWGARLGDKLGRLYESAQSTLVTQQAFELEQRATLIGVDEDYAV
ILPSLAGSAAGPNSGAARFATSAQQAALAGVLRETIERELKSQTGKRVPGKGERLWVGPY
RDPLQNTPVISAVSAYYEGDKPVTLISASIPLNVLAARIAPPGSAGATLLMAPDRRILVS
SAALDAQTGAMLQRAVAATPPHVFHYEREGAIFYEPLMPGFGSLVGYVPWGGLAAALGWQ
LAVIGSLAFLVMLAIALTARLFGLRLLRSAFAETSRALESDTLNHILVSATPIGLCIVRR
SDYSILTANALAAELLQIEPGTSRLPPHIAAGFLPRAPEQTSAAAFARIAAFVAPAQPPS
QPATLVPANAQATAAPEAGAAPAQFLQITYAPARYAGEHVLFCAILDVTAQHALEQQLRD
AQQASDAMMRARTNFFAAMSHEIRTPLNALLGNLELFARTPGLEAHAQRLAALNVAGDAL
RRVVNDILDFSKIDAGEMLLVREPFPLLEAFESIALSYAAMAGDRPVRFFSLLSPALDRT
VVGDRMRIAQVINNLLSNAFKFTSSGKIMLQADLIDDAQGRPILNCRVSDSGPGMTQELV
TRLFKPFVQGEAGASRGAESTGLGLVICARLCQLMGGTISAESVVSVGSVFNVSIPLAAP
PDEKPARPAPVVEKRGMLLALCQDSQVAELFRRWLEHFGWSAHVVPALAAARAWLQVNRP
TALIVSGAYDLDVIASLRALQPVPAVWVTRAGPQRPQMRAEGVLEVTEFSGTAVRTAIEL
AVEGKPVAAPCEVPAAPRMDSAAAPVLTTHPALQGLTILVAEDNPLIQTLIAEQLATLGC
APTIAGDGRMALGFFERTHFDVVLTDIHMPAMDGFEFLAALRKLDADVPVLAFSAVAENQ
EAQSWHERGFSGYVSKPASLGELQAALLAVAPAVPEKAAPGAAPASVAATGARLAADEKA
RYTAMLKEHLKNDLPRLLAIVDEEDRQALAGWAHSASGAFVIVQEPRFVEECRQLQRLCN
DSESWTTEMDERAVSLHEALCDHYGMDEPSTH