Protein Info for H281DRAFT_03434 in Paraburkholderia bryophila 376MFSha3.1

Annotation: tyrosine-protein kinase Etk/Wzc

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 772 transmembrane" amino acids 33 to 56 (24 residues), see Phobius details amino acids 445 to 465 (21 residues), see Phobius details PF02706: Wzz" amino acids 25 to 109 (85 residues), 41.7 bits, see alignment E=2.4e-14 PF13807: GNVR" amino acids 389 to 467 (79 residues), 61 bits, see alignment E=1.7e-20 TIGR01007: capsular exopolysaccharide family" amino acids 551 to 754 (204 residues), 151.6 bits, see alignment E=1e-48 PF13614: AAA_31" amino acids 582 to 701 (120 residues), 31.3 bits, see alignment E=3.9e-11

Best Hits

KEGG orthology group: None (inferred from 93% identity to bug:BC1001_5440)

Predicted SEED Role

"Tyrosine-protein kinase Wzc (EC 2.7.10.2)" in subsystem Colanic acid biosynthesis (EC 2.7.10.2)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.10.2

Use Curated BLAST to search for 2.7.10.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MJ37 at UniProt or InterPro

Protein Sequence (772 amino acids)

>H281DRAFT_03434 tyrosine-protein kinase Etk/Wzc (Paraburkholderia bryophila 376MFSha3.1)
VDYYPLNSLPATASTERGQLSPSAMLRLMRDHIWEIVLTTVVVVSLAAAYLLIASPIYSA
DVLIRVDPPEPNALGLALQNQENLPPPAPSTVTEMGVMRSRSVLEPVIQRFRFDVSVTPH
KLPLLGDIAEKFATPGEPSRPWLGLKSYAWGGEQVKIGTLDVPKDLEEEKMTLVAGEDNT
YELRGPQDQVFLHGVIGKQVSSNGISMRVDELVARPGTEFTVVRWNAVDAIKRFDATIKV
SDKVKDSGLLQIEYTDKSAAKAAEVANALGQQYLATAIASRQLNDTTTLAFINGELPRLL
ADLRKAEEALKAFRANSQSMQPTAEAQAYLQGGLDIDRQIATLQLQRTQLLERYTPQSRW
VQSVDTQLAQLKNAKASFDGHFNGMPASERSSVDLIRAQKVAETIYLGMVQKAEQLQVRR
ASTTGGAHVVDEAITPHRPVKPKPILVLPGGLVLGLVSGVVLVFMRRHVLTGVTDPRYVE
RRMSVPVFGEILFSQQQLLLDRTNAGAKSLPGAAARAGLPQPATGGVPEIQVAGGGTKVL
AERFPNDTSVEALRAVRTSLARDLAHSRNNILMVIGPTPSAGKSFVAANIATLQAEIGAR
VLLIDADMRRGHLASLFNQNNRGGLSEVLSDRMPLRNALRHTGIDGLSFMSCGSRPDNPA
ALLARPRFKEVLERLSGQFDLVIFDTPPFLAVTDASIIASEAGASLLVLRSGMQSEEEIE
DTVKKMERADGRIAGAVFNGIPLRRSTRTYGYATNYASDYGDADATSGSLRT