Protein Info for H281DRAFT_03427 in Paraburkholderia bryophila 376MFSha3.1

Annotation: cytochrome bo3 quinol oxidase subunit 1 apoprotein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 671 transmembrane" amino acids 16 to 37 (22 residues), see Phobius details amino acids 58 to 81 (24 residues), see Phobius details amino acids 101 to 125 (25 residues), see Phobius details amino acids 144 to 168 (25 residues), see Phobius details amino acids 189 to 212 (24 residues), see Phobius details amino acids 226 to 253 (28 residues), see Phobius details amino acids 278 to 302 (25 residues), see Phobius details amino acids 314 to 333 (20 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 379 to 402 (24 residues), see Phobius details amino acids 414 to 435 (22 residues), see Phobius details amino acids 454 to 474 (21 residues), see Phobius details amino acids 493 to 517 (25 residues), see Phobius details amino acids 595 to 631 (37 residues), see Phobius details TIGR02843: cytochrome o ubiquinol oxidase, subunit I" amino acids 2 to 651 (650 residues), 1129.3 bits, see alignment E=0 PF00115: COX1" amino acids 56 to 501 (446 residues), 495.8 bits, see alignment E=5.7e-153

Best Hits

Swiss-Prot: 67% identical to QOX1_ACEAC: Ubiquinol oxidase subunit 1 (cyaA) from Acetobacter aceti

KEGG orthology group: K02298, cytochrome o ubiquinol oxidase subunit I [EC: 1.10.3.-] (inferred from 96% identity to bug:BC1001_5434)

MetaCyc: 63% identical to cytochrome bo terminal oxidase subunit I (Pseudomonas putida KT2440)
RXN0-5268 [EC: 7.1.1.3]

Predicted SEED Role

"Cytochrome O ubiquinol oxidase subunit I (EC 1.10.3.-)" in subsystem Terminal cytochrome O ubiquinol oxidase or Terminal cytochrome oxidases (EC 1.10.3.-)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 7.1.1.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MGP6 at UniProt or InterPro

Protein Sequence (671 amino acids)

>H281DRAFT_03427 cytochrome bo3 quinol oxidase subunit 1 apoprotein (Paraburkholderia bryophila 376MFSha3.1)
MLGNLTLSAIPFDQPIIMGAGALMIVMVLAVVATLTRLHKWKWLWHEWLTSVDHKKIGVM
YIVVAVLMLVRGFVDAVMMRLQLALAYHSPGYLPPHHYDQIFTAHGVIMIFFMAMALMVG
LFNLVVPLQIGARDVAFPFLNSLSFWMTAISAILMNLSLVIGEFAQVGWLAYPPLSELKF
SPGVGVDYYIWSLQLSGVGTLITAINFFVTIVRMRAPGMTLMKMPVFTWTALCSNVLIMA
TFPILTVALALLGLDRYMGMHFFTNEAGGNAMLYLNLIWAWGHPEVYILVLPAFGIYSEV
IATFSKKPLFGYRTMVYATCAIMVLAFLVWLHHFFTMGSGADVNAFFGIMTMVIAIPTGV
KIFNWLFTIYRGRLEFSAPVLWTIGFMITFTIGGMTGVMMAIPGADFVLHNSLFLIAHFH
NAIIGGVVFGYLAGFHYWFPKAFGFKLNEKLGKCAFWCWFVGFYASFMPLYVLGFMGVTR
RLNHYDNPAWHPWMIAAACGVALIAVGVVFQVAQVWVSVANRNKPEYRDVTGDPWNGRTL
EWATASPPPVYNFAIIPTVHELDAYAHMKETTSGLAKAPANQAYQDIHMPSNTSAGLLIG
LFSLVLGFAGVWHITWLAVAALLAIVATLIARSFGDNDGYYISADTVREIESKRGPAAAA
VQSREFEAVEA