Protein Info for H281DRAFT_03394 in Paraburkholderia bryophila 376MFSha3.1

Annotation: PAS/PAC sensor signal transduction histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 734 transmembrane" amino acids 20 to 54 (35 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 89 to 108 (20 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 123 to 237 (115 residues), 71.3 bits, see alignment E=3.9e-24 amino acids 240 to 365 (126 residues), 36.7 bits, see alignment E=2.1e-13 PF00989: PAS" amino acids 123 to 228 (106 residues), 45.6 bits, see alignment E=2.3e-15 amino acids 243 to 355 (113 residues), 24.4 bits, see alignment E=8.9e-09 PF08448: PAS_4" amino acids 127 to 233 (107 residues), 40.6 bits, see alignment E=9.2e-14 amino acids 250 to 360 (111 residues), 32.5 bits, see alignment E=3.1e-11 PF13426: PAS_9" amino acids 129 to 229 (101 residues), 37.2 bits, see alignment E=1e-12 PF08447: PAS_3" amino acids 266 to 352 (87 residues), 53.7 bits, see alignment E=7.4e-18 amino acids 394 to 473 (80 residues), 32.7 bits, see alignment E=2.5e-11 PF02518: HATPase_c" amino acids 619 to 726 (108 residues), 79.2 bits, see alignment E=1.1e-25

Best Hits

KEGG orthology group: None (inferred from 66% identity to bph:Bphy_5692)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MI19 at UniProt or InterPro

Protein Sequence (734 amino acids)

>H281DRAFT_03394 PAS/PAC sensor signal transduction histidine kinase (Paraburkholderia bryophila 376MFSha3.1)
MKTYPSVLLAANRDTSIPMALAALIALVVFLIDALTPLDIAIAVLYVVVVLLVASTNNRA
VTVATTWGCVALTLLGFVMSHEGGYLNGAAARCLVSLVAIGTTSVLSLRNQAAATTLQEQ
IQLLNLAHDAIVVHDMNDRITFWNHGAEALYGWTAQQALGQSIHQLTQTSFPVSPEDIKD
ELLRTNRWHGELQRVRRDGRVVAVSTRAALWRDATGTPRAVLATNNDITRRKEMEARVQR
QQEELRATIDAIPGMVWSSSGDGTLTFINRRWTDMGVTLEEGGSGADVWSAIVHPADLPQ
MQRAWRSAIATGASFENVSRIRTGTGAYRWMHLGAEPLRDEAGAILRWYGVNTDIEDRKQ
AEQALERSEAFLADTQRLSRTGSIATHFPDASMWWSDESYRIFEYSREVVPSFDAILART
HPADVATVRGAFEQAKVGAALVDVKYRLAMPDGSVKYVHYVAHLTRPQSGGTEYVGALMD
ITETTLAQEALARSSAELAHVTRITMLGELAASIAHEVTQPIAAVVACGGAALRWLNRPT
PELDEATRSVTQIVRDAKRAGEIIQRIRAMAKKRDSVPAPVALNAIVTESAELMRREFEW
HAVEVQWDLDEPSPEACCDRVELQQVLINLLMNSVQAMADVSGPRKLRIATGMFDPGHAL
VSVQDSGTGISEDNADRMFSTFFTTKSEGMGMGLSICRSIVEAHGGRIWAESPATGGALL
QFILPIDDGRCHEQ