Protein Info for H281DRAFT_03376 in Paraburkholderia bryophila 376MFSha3.1

Annotation: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 162 to 178 (17 residues), see Phobius details PF08240: ADH_N" amino acids 25 to 129 (105 residues), 109.5 bits, see alignment E=1.2e-35 PF16912: Glu_dehyd_C" amino acids 151 to 318 (168 residues), 39.5 bits, see alignment E=6.5e-14 PF00107: ADH_zinc_N" amino acids 169 to 294 (126 residues), 70.6 bits, see alignment E=1.9e-23

Best Hits

KEGG orthology group: None (inferred from 94% identity to bpy:Bphyt_5476)

Predicted SEED Role

"Threonine dehydrogenase and related Zn-dependent dehydrogenases" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MH29 at UniProt or InterPro

Protein Sequence (335 amino acids)

>H281DRAFT_03376 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase (Paraburkholderia bryophila 376MFSha3.1)
MLSVICESPGVLRREDREPPRRADGEVLLRVSRVGICGTDMHIYSGNQPYLQYPRVMGHE
LSAIVAEADPGAHVAPGDAVYVMPYLSCGQCIACRQGKTNCCVNIKVLGVHRDGALTEYL
SVPAQFVHKADGVTLDQAAMLEFLAIGAHAVRRADVSAGQRVLVVGAGPIGMAAMLFANL
RGGRVSCLDTRADRLAFCREHIAVSTVQIGPNDVQELAALTDGEFFDVVFDATGNVNAMN
RGFEFIAHGGKYVLISIVPGQITFSDPEFHKREATLLGSRNATAEDFETVLEAMRAGRIP
DKALNTDRMSLADVPTEFPKLMEPGRTVVKALVEC