Protein Info for H281DRAFT_03347 in Paraburkholderia bryophila 376MFSha3.1

Annotation: formiminoglutamase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01227: formimidoylglutamase
  • amino acids 10 to 320 (311 residues), 301.6 bits, E=3.1e-94
• PF00491: Arginase
  • amino acids 44 to 321 (278 residues), 181.1 bits, E=1.7e-57

Best Hits

Swiss-Prot: 92% identical to HUTG_PARXL: Formimidoylglutamase (hutG) from Paraburkholderia xenovorans (strain LB400)

KEGG orthology group: K01479, formiminoglutamase [EC: 3.5.3.8] (inferred from 92% identity to bxe:Bxe_B2046)

Predicted SEED Role

"Formiminoglutamase (EC 3.5.3.8)" in subsystem Histidine Degradation (EC 3.5.3.8)

MetaCyc Pathways

• L-histidine degradation I (4/4 steps found)

KEGG Metabolic Maps

• Histidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.8

Protein Sequence (322 amino acids)

>H281DRAFT_03347 formiminoglutamase (Paraburkholderia bryophila 376MFSha3.1)
MRVPFDGKVWAGRSDDGEPGDTRRVFNQVTPFGSAQQVQRDVPVIVGFSSDEGVRRNQGR
IGAAHAPKELRRVLAGLPAKAAIAALADAGDVVCDDGDLEAAQAELAHVVSEVLASGARP
LVFGGGHEVAWGTYSGLRLHQQREAGNQATLLISRKLLIINFDAHFDLRQKRPANSGTPF
DQIALDCEERGVSFNYVCFGISDLGNTASLFAHAERLGVRYVLDVDMQETQLPQRLNELQ
KLLDAADDVYLTIDLDVLPAATAPGVSAPAALGVPLSVVEAMVLRVRASGKLRASDIAEY
NPTLDQDRRTARAAARLAYRLL