Protein Info for H281DRAFT_03233 in Paraburkholderia bryophila 376MFSha3.1
Annotation: cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 93% identity to bgf:BC1003_5324)Predicted SEED Role
"cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases" in subsystem cAMP signaling in bacteria
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5MHQ2 at UniProt or InterPro
Protein Sequence (428 amino acids)
>H281DRAFT_03233 cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases (Paraburkholderia bryophila 376MFSha3.1) VPEEGTRWTKSSSGVPILNQQRTPWTRTAAPGEVIYSEGFLGDAVIYVIADGKVEISTQC DEKKVILATLGKGEFFGEAALLPPEPRAHTAKALSFCQLTAIAGGIVEEELERVSPLLRH IVRTMIRRVKKKDDILATNTHADFLPGVLSYAHVLSLMAGAEPNDRFDGRARRPQNEEIS IPLSEVIKKCNAIAGHSRPHVMAMLKRMEKLNLVSIEGGRSERLNNTSGRYSASDGAAGR QLVTFDAVKITERAQQVADHDLDVSISSELELIELDDLEALIGVDRKVILNKLSHAEIAE DIFAFRKTKVLNYVEEKGLSYFSRRTARGAGELKSLDDLEFVDQRTLFEAVSAFDTYDLA KLLSASEGQPIDERLQSVMTEARKKEVSWVMRREIKIDPVEIIEIEQRFLDTVRALKSPV ANTAPAES