Protein Info for H281DRAFT_03195 in Paraburkholderia bryophila 376MFSha3.1

Annotation: D-methionine transport system permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 52 to 76 (25 residues), see Phobius details amino acids 82 to 105 (24 residues), see Phobius details amino acids 138 to 166 (29 residues), see Phobius details amino acids 187 to 207 (21 residues), see Phobius details PF00528: BPD_transp_1" amino acids 46 to 217 (172 residues), 76.7 bits, see alignment E=9.8e-26

Best Hits

Swiss-Prot: 51% identical to METI_VIBCH: Probable D-methionine transport system permease protein MetI (metI) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02072, D-methionine transport system permease protein (inferred from 98% identity to bgf:BC1003_5281)

MetaCyc: 48% identical to L-methionine/D-methionine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
RXN0-4522 [EC: 7.4.2.11]; 7.4.2.11 [EC: 7.4.2.11]; TRANS-RXN-383 [EC: 7.4.2.11]; TRANS-RXN0-510 [EC: 7.4.2.11]; TRANS-RXN0-511 [EC: 7.4.2.11]

Predicted SEED Role

"Methionine ABC transporter permease protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MIH3 at UniProt or InterPro

Protein Sequence (218 amino acids)

>H281DRAFT_03195 D-methionine transport system permease protein (Paraburkholderia bryophila 376MFSha3.1)
MSDLWLSELVGAIRDTVVMVGVSAVIAALVGIPLALVLVTTTRGGIFEKRAVNSTLGALV
NAFRSTPFIILLVALLPLTRLLIGTTIGVWAAIVPLSIAAIPFLARVAEVSLREVDRGLI
EAAQAMGAQRRHIIWHVLLPEALPGIVGGFTITVVAMIGSSAMAGAVGAGGLGDLAIRYG
YQRFDTTVMVTVIVLLIAIVTTVQLVGDRFVRRLAQRA